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人工智能在神经科学中的应用:机遇、挑战与政策影响。

Artificial intelligence in neurology: opportunities, challenges, and policy implications.

机构信息

Systems Neuroscience Division, Max-Planck-Institute for Biological Cybernetics, Tübingen, Germany.

Virtual Diagnostics Team, QuantCo Inc., Cambridge, MA, USA.

出版信息

J Neurol. 2024 May;271(5):2258-2273. doi: 10.1007/s00415-024-12220-8. Epub 2024 Feb 17.

Abstract

Neurological conditions are the leading cause of disability and mortality combined, demanding innovative, scalable, and sustainable solutions. Brain health has become a global priority with adoption of the World Health Organization's Intersectoral Global Action Plan in 2022. Simultaneously, rapid advancements in artificial intelligence (AI) are revolutionizing neurological research and practice. This scoping review of 66 original articles explores the value of AI in neurology and brain health, systematizing the landscape for emergent clinical opportunities and future trends across the care trajectory: prevention, risk stratification, early detection, diagnosis, management, and rehabilitation. AI's potential to advance personalized precision neurology and global brain health directives hinges on resolving core challenges across four pillars-models, data, feasibility/equity, and regulation/innovation-through concerted pursuit of targeted recommendations. Paramount actions include swift, ethical, equity-focused integration of novel technologies into clinical workflows, mitigating data-related issues, counteracting digital inequity gaps, and establishing robust governance frameworks balancing safety and innovation.

摘要

神经疾病是导致残疾和死亡的主要原因,需要创新、可扩展和可持续的解决方案。随着世界卫生组织在 2022 年通过部门间全球行动计划,大脑健康已成为全球优先事项。与此同时,人工智能 (AI) 的快速发展正在彻底改变神经科学研究和实践。本研究通过对 66 篇原始文章的范围界定性回顾,探讨了 AI 在神经病学和大脑健康中的价值,为新兴的临床机会和未来趋势在整个护理轨迹(预防、风险分层、早期发现、诊断、管理和康复)进行了系统分类。AI 在推进个性化精准神经科学和全球大脑健康指令方面的潜力取决于通过有针对性地提出建议,在四个核心领域——模型、数据、可行性/公平性和监管/创新——解决核心挑战。首要行动包括迅速、合乎道德且关注公平地将新技术纳入临床工作流程,减轻数据相关问题,克服数字不平等差距,并建立平衡安全和创新的稳健治理框架。

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