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类鼻疽病病例报告:一个真正的伪装者。

A Case Report of Whitmore's Disease: A True Masquerader.

作者信息

Patil Chandrashekar, Mangalagiri Nikhitha, Ajmera Prakash, Kumar Ks Prashanth, Reddy Haritha

机构信息

Radiology, Mallareddy Medical College for Women, Hyderabad, IND.

Cardiology, Malla Reddy Narayana Multispeciality Hospital, Hyderabad, IND.

出版信息

Cureus. 2024 Jan 16;16(1):e52409. doi: 10.7759/cureus.52409. eCollection 2024 Jan.

DOI:10.7759/cureus.52409
PMID:38371114
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10869667/
Abstract

Melioidosis is an uncommon bacterial infection that is endemic to countries like Southeast Asia and Northern Australia but less common in temperate zones than when seen in returned travelers. This disease can affect almost every organ, with the lung being the most common organ to be involved. Here, we present a 21-year-old diabetic male who came with complaints of fever, nonproductive cough, and sore throat with grade III-IV shortness of breath. Laboratory investigations revealed hypokalemia and isolates of on blood culture and sensitivity. High-resolution computed tomography (HRCT) of the chest showed widespread, variable-sized nodules with central cavitations diffusely scattered in bilateral lungs.

摘要

类鼻疽是一种不常见的细菌感染,在东南亚和澳大利亚北部等国家为地方病,但在温带地区比在归国旅行者中更为少见。这种疾病几乎可累及每个器官,其中肺部是最常受累的器官。在此,我们报告一名21岁的糖尿病男性患者,他因发热、干咳、咽痛伴III-IV级呼吸急促前来就诊。实验室检查发现低钾血症,血培养及药敏试验分离出[具体病菌未给出]。胸部高分辨率计算机断层扫描(HRCT)显示双侧肺野广泛分布着大小不一的结节,伴有中央空洞。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c09/10869667/33ee2de336a5/cureus-0016-00000052409-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c09/10869667/33ee2de336a5/cureus-0016-00000052409-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c09/10869667/33ee2de336a5/cureus-0016-00000052409-i01.jpg

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A Case Report of Whitmore's Disease: A True Masquerader.类鼻疽病病例报告:一个真正的伪装者。
Cureus. 2024 Jan 16;16(1):e52409. doi: 10.7759/cureus.52409. eCollection 2024 Jan.
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引用本文的文献

1
Melioidosis molecular diagnostics: An update.类鼻疽分子诊断学:最新进展
Virulence. 2025 Dec;16(1):2505698. doi: 10.1080/21505594.2025.2505698. Epub 2025 Jun 14.

本文引用的文献

1
Radiology of Chronic Cavitary Infections.慢性空洞性感染的放射学。
J Thorac Imaging. 2018 Sep;33(5):334-343. doi: 10.1097/RTI.0000000000000346.
2
Pulmonary aspergillosis.肺曲霉病
Diagn Interv Imaging. 2015 May;96(5):435-42. doi: 10.1016/j.diii.2015.01.005. Epub 2015 Mar 6.
3
Thoracic radiologic manifestations of melioidosis.类鼻疽的胸部放射学表现。
Curr Probl Diagn Radiol. 2012 Nov-Dec;41(6):199-209. doi: 10.1067/j.cpradiol.2012.01.001.
4
Risk factors for recurrent melioidosis in northeast Thailand.泰国东北部类鼻疽复发的危险因素。
Clin Infect Dis. 2006 Oct 15;43(8):979-86. doi: 10.1086/507632. Epub 2006 Sep 1.
5
Pathogenesis of and immunity to melioidosis.类鼻疽的发病机制与免疫
Acta Trop. 2000 Feb 5;74(2-3):201-10. doi: 10.1016/s0001-706x(99)00071-6.
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Pulmonary melioidosis: clinical-radiologic correlation in 183 cases in northeastern Thailand.
Radiology. 1988 Mar;166(3):711-5. doi: 10.1148/radiology.166.3.3340766.
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Septicaemic melioidosis: a review of 50 cases from Malaysia.败血症型类鼻疽:马来西亚50例病例综述。
Trans R Soc Trop Med Hyg. 1992 Nov-Dec;86(6):683-5. doi: 10.1016/0035-9203(92)90191-e.