Straus D, Gilbert W
Mol Cell Biol. 1985 Dec;5(12):3497-506. doi: 10.1128/mcb.5.12.3497-3506.1985.
We report the sequence of the single chicken triosephosphate isomerase gene and its flanking regions. The 3-kilobase-long gene is composed of seven similarly sized exons and six introns. By using crystallographic and sequence data, we argue that this ancient gene was originally assembled from the genetic antecedents of exons.
我们报道了单个鸡磷酸丙糖异构酶基因及其侧翼区域的序列。这个长达3千碱基的基因由七个大小相似的外显子和六个内含子组成。通过使用晶体学和序列数据,我们认为这个古老的基因最初是由外显子的遗传前身组装而成的。