Faculty of Medicine, Saint Joseph University of Beirut, Beirut, Lebanon.
Faculty of Medical Sciences, Lebanese University, Hadat, Lebanon.
Support Care Cancer. 2024 Feb 20;32(3):172. doi: 10.1007/s00520-024-08380-y.
This cross-sectional study aimed to investigate the prevalence and characteristics of supplement usage among cancer patients and explore its potential associations with anxiety, excessive daytime sleepiness, and overall quality of life.
Cancer patients receiving specific care at Hôtel Dieu de France University Hospital, Beirut, were enrolled between April and June 2023. In face-to-face interviews, participants were asked to complete a questionnaire consisting of sociodemographic information, supplement usage details, and cancer-related variables. Three validated surveys (Epworth Sleepiness Scale, GAD-7, and EORTC-QLQ-C15-PAL) were employed to assess excessive daytime sleepiness, anxiety, and overall quality of life. Statistical analyses, including chi-square tests, t-tests, and multiple regression models, were conducted to examine associations between supplement use and other variables.
A total of 202 participants were interviewed. Fifty-two percent reported regular use of supplements following their cancer diagnosis, with vitamin D being the most commonly used supplement. Using multivariate logistic regression, supplement use was associated with being female, having lower educational levels, having a longer duration since cancer diagnosis, and having a poor overall quality of life. The multivariate logistic regression showed no significant correlation between supplement use and excessive daytime sleepiness and anxiety.
This study highlights a high prevalence of supplement usage among cancer patients in Lebanon, indicating a rising interest in alternative therapies aimed at enhancing quality of life. Larger prospective studies are needed to assess the relation between supplement intake and excessive daytime sleepiness and anxiety and establish clear guidelines pertaining to supplement use in cancer patients.
本横断面研究旨在调查癌症患者补充剂使用的流行情况和特征，并探讨其与焦虑、日间嗜睡和整体生活质量的潜在关联。
2023 年 4 月至 6 月，在贝鲁特法国医院接受特定护理的癌症患者参与了这项研究。在面对面访谈中，要求参与者完成一份包含社会人口统计学信息、补充剂使用详情和癌症相关变量的问卷。采用三个经过验证的调查工具（Epworth 嗜睡量表、GAD-7 和 EORTC-QLQ-C15-PAL）评估日间嗜睡、焦虑和整体生活质量。采用卡方检验、t 检验和多变量回归模型进行统计分析，以检验补充剂使用与其他变量之间的关联。
共访谈了 202 名参与者。52%的参与者报告在癌症诊断后定期使用补充剂，其中维生素 D 是最常用的补充剂。采用多变量逻辑回归分析，补充剂使用与女性、较低的教育水平、癌症诊断后时间较长以及整体生活质量较差有关。多变量逻辑回归显示，补充剂使用与日间嗜睡和焦虑之间无显著相关性。
本研究强调了黎巴嫩癌症患者补充剂使用的高流行率，表明人们对旨在提高生活质量的替代疗法的兴趣日益浓厚。需要进行更大规模的前瞻性研究，以评估补充剂摄入与日间嗜睡和焦虑之间的关系，并制定针对癌症患者补充剂使用的明确指南。
