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空气污染与 16 个波兰城市因 COPD 和哮喘导致的急诊住院之间的关联:基于人群的研究。

The association between air pollutions and emergency hospitalizations due to COPD and asthma across 16 Polish cities: population-based study.

机构信息

Jagiellonian University Medical College, Kraków, Poland (Department of Environmental Health).

Agency for Health Technology Assessment and Tariff System, Warsaw, Poland.

出版信息

Int J Occup Med Environ Health. 2024 Mar 5;37(1):110-127. doi: 10.13075/ijomeh.1896.02197. Epub 2024 Feb 21.

Abstract

OBJECTIVES

In recent years numerous initiatives aimed at reducing air pollution have been undertaken in Poland. The general objective was to examine the correlation between air pollution measured by the level of particulate matter ≤10 μm in diameter (PM) and emergency hospitalizations due to chronic obstructive pulmonary disease (COPD) and asthma in 16 Polish cities (capitals of the regions).

MATERIAL AND METHODS

The authors aimed to diagnose the situation across 16 cities over a 5‑year period (2014-2019). Data on the number of hospitalizations was retrieved from the national public insurance system, the National Health Fund. A total number of 22 600 emergency hospitalizations was analyzed (12 000 and 10 600 in 2014 and 2019, respectively). The data on air pollution was accessed via the public register of the Chief Inspectorate for Environmental Protection air quality database. The authors of this article have used the data on PM daily exposure in each of the 16 cities in 2014 and 2019. Statistical methods included: non-parametric tests, a 2-stage modelling approach for time-series data, and multivariate meta-analysis of the results.

RESULTS

The results indicated that there was a statistically significant decrease in PM concentration in 2019 in comparison to 2014 in all cities, mainly in the autumn and winter season. However, the correlation between the improvement in the air quality and a decrease in emergency hospitalizations due to asthma and COPD turned out to not be as strong as expected. The authors observed a strong correlation between PM concentrations and hospitalizations due to asthma and COPD, but only when air quality norms were significantly above acceptable levels.

CONCLUSIONS

Air pollution measured by PM concentration might be used as one of the predictors of the asthma and COPD emergency hospitalization risk, yet other factors like respiratory tract infection, health care organizational aspect, patient self-control, compliance and comorbidities should also be taken into consideration. Int J Occup Med Environ Health. 2024;37(1):110-27.

摘要

目的

近年来,波兰开展了多项旨在减少空气污染的举措。本研究的总体目标是检验在波兰 16 个城市(地区首府)中,直径≤10μm 的颗粒物(PM)污染水平与慢性阻塞性肺疾病(COPD)和哮喘急诊住院率之间的相关性。

材料与方法

本研究旨在分析 16 个城市 5 年(2014-2019 年)的数据。通过国家公共保险系统(国家卫生基金)获取住院人数数据。共分析了 22600 例急诊住院病例(2014 年和 2019 年分别为 12000 例和 10600 例)。空气污染数据通过公共环境保护总局空气质量数据库获取。本研究使用了 2014 年和 2019 年 16 个城市中 PM 每日暴露量的数据。统计方法包括:非参数检验、时间序列数据的两阶段建模方法和结果的多元荟萃分析。

结果

结果表明,与 2014 年相比,2019 年所有城市的 PM 浓度均呈统计学显著下降,主要集中在秋季和冬季。然而,空气质量改善与哮喘和 COPD 急诊住院率下降之间的相关性并不像预期的那样强。研究人员观察到 PM 浓度与哮喘和 COPD 住院之间存在很强的相关性,但仅在空气质量标准明显高于可接受水平时才会出现这种相关性。

结论

PM 浓度可作为哮喘和 COPD 急诊住院风险的预测因素之一,但还应考虑其他因素,如呼吸道感染、医疗保健组织方面、患者自我控制、依从性和合并症。国际职业医学与环境卫生杂志。2024;37(1):110-27.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44fa/10959279/22cb689ece50/ijomeh-37-110-g001.jpg

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