Podleski W K
Allergy. 1985 Apr;40(3):166-72. doi: 10.1111/j.1398-9995.1985.tb00212.x.
Antibody-dependent, allergic autocytotoxicity (ACT) is an in vitro process through which WBC from patients and/or controls, passively sensitized with RAST positive serum, are damaged in the presence of corresponding food antigens. Studies among 13 patients, sensitive to cow milk, corn and wheat, and 13 asymptomatic controls revealed that antibody-dependent ACT is mediated by thermolabile cytotoxic factor, presumably IgE antibody. The resultant cellular interactions might contribute to the induction of the autoimmune response.
抗体依赖性过敏自身细胞毒性（ACT）是一种体外过程，在此过程中，用放射性变应原吸附试验（RAST）阳性血清被动致敏的患者和/或对照的白细胞，在相应食物抗原存在的情况下会受到损伤。对13名对牛奶、玉米和小麦敏感的患者以及13名无症状对照进行的研究表明，抗体依赖性ACT由不耐热细胞毒性因子介导，推测为IgE抗体。由此产生的细胞相互作用可能有助于自身免疫反应的诱导。
