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可乐果种子的抗肝毒性成分。

Antihepatoxic constituents of Garcinia kola seeds.

作者信息

Iwu M M

出版信息

Experientia. 1985 May 15;41(5):699-700. doi: 10.1007/BF02007729.

DOI:10.1007/BF02007729
PMID:3838940
Abstract

Kolaviron, a fraction of defatted methanolic extract and biflavanones of Garcinia kola seeds significantly antagonized the lethal poisoning of mice with phalloidin. Garcinia biflavanones GB1, GB2 and kolaflavanone were isolated as the active constituents.

摘要

可乐果素是可乐果种子脱脂甲醇提取物和双黄酮的一部分，能显著拮抗小鼠因鬼笔环肽所致的致命中毒。分离出双黄酮GB1、GB2和可乐黄酮作为活性成分。

相似文献

1
Antihepatoxic constituents of Garcinia kola seeds.可乐果种子的抗肝毒性成分。
Experientia. 1985 May 15;41(5):699-700. doi: 10.1007/BF02007729.
2
Evaluation of the antihepatotoxic activity of the biflavonoids of Garcinia kola seed.可乐果种子双黄酮的抗肝毒性活性评估。
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Capillary electrophoresis determination of biflavanones from Garcinia kola in three traditional African medicinal formulations.毛细管电泳法测定三种非洲传统药用制剂中可乐果的双黄酮类化合物。
Planta Med. 2002 May;68(5):440-4. doi: 10.1055/s-2002-32091.
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Chemoprevention of 2-acetylaminofluorene-induced hepatotoxicity and lipid peroxidation in rats by kolaviron--a Garcinia kola seed extract.可乐维隆（一种可乐果种子提取物）对2-乙酰氨基芴诱导的大鼠肝毒性和脂质过氧化的化学预防作用
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[Phalloidin antagonists. 2. Protective effect of disilybine in phalloidin poisoning of isolated hepatocytes].[鬼笔环肽拮抗剂。2. 二氢杨梅素对离体肝细胞鬼笔环肽中毒的保护作用]
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Possible anti-atherogenic effect of kolaviron (a Garcinia kola seed extract) in hypercholesterolaemic rats.可乐维隆（可乐果种子提取物）对高胆固醇血症大鼠可能具有的抗动脉粥样硬化作用。
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[Anti-phalloidine activity of the silymarins silybine and disilybine].[水飞蓟宾和双水飞蓟宾的抗鬼笔环肽活性]
Arzneimittelforschung. 1975 Mar;25(3):392-3.

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本文引用的文献

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Stem bark alkaloids of Rauwolfia vomitoria.罗芙木中的茎皮生物碱。
Planta Med. 1982 Jun;45(2):105-11. doi: 10.1055/s-2007-971256.
2
Kolanone, a novel polyisoprenylated benzophenone with antimicrobial properties from the fruit of Garcinia kola.可乐酮，一种从可乐果中提取的具有抗菌特性的新型聚异戊烯基化二苯甲酮。
Planta Med. 1982 Feb;44(2):78-81. doi: 10.1055/s-2007-971406.
3
Prevention of silybin of phalloidin-induced acute hepatoxicity.水飞蓟宾对鬼笔环肽诱导的急性肝毒性的预防作用。
可乐维隆（一种来自……的生物类黄酮）在心血管疾病管理中的作用：一项系统综述。
Heliyon. 2024 Feb 29;10(5):e27333. doi: 10.1016/j.heliyon.2024.e27333. eCollection 2024 Mar 15.
4
Kolaviron modulates angiogenesis, apoptosis and inflammatory signaling in rat model of testosterone propionate-induced benign prostate hyperplasia.科拉维酮调节丙酸睾酮诱导的良性前列腺增生大鼠模型中的血管生成、细胞凋亡和炎症信号通路。
Inflammopharmacology. 2023 Aug;31(4):2121-2131. doi: 10.1007/s10787-023-01171-7. Epub 2023 Mar 7.
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Kolaviron protects against cognitive deficits and cortico-hippocampal perturbations associated with maternal deprivation in rats.可乐维隆可预防与大鼠母体剥夺相关的认知缺陷和皮质-海马扰动。
Anat Cell Biol. 2020 Mar;53(1):95-106. doi: 10.5115/acb.19.160. Epub 2019 Mar 31.
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Kolaviron Protects the Prefrontal Cortex and Hippocampus against Histomorphological and Neurobehavioural Changes in Cuprizone Model of Multiple Sclerosis.可乐维隆可保护前额叶皮质和海马体免受多发性硬化症铜离子螯合剂模型中的组织形态学和神经行为学变化的影响。
Malays J Med Sci. 2018 Mar;25(2):50-63. doi: 10.21315/mjms2018.25.2.6. Epub 2018 Apr 27.
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Kolaviron and selenium reduce hydrogen peroxide-induced alterations of the inflammatory response.可乐维隆和硒可减轻过氧化氢诱导的炎症反应改变。
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