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Complete nucleotide sequence of hepatic 5-aminolaevulinate synthase precursor.

作者信息

Borthwick I A, Srivastava G, Day A R, Pirola B A, Snoswell M A, May B K, Elliott W H

出版信息

Eur J Biochem. 1985 Aug 1;150(3):481-4. doi: 10.1111/j.1432-1033.1985.tb09047.x.

DOI:10.1111/j.1432-1033.1985.tb09047.x
PMID:3839458
Abstract

Chick embryo liver mitochondrial matrix protein, 5-aminolaevulinate synthase, is synthesised initially as a larger cytosolic precursor. In this report we present the complete nucleotide sequence of a cDNA clone coding for the precursor together with corresponding confirmatory amino acid sequence of peptides derived from purified mature mitochondrial enzyme. The deduced amino acid sequence shows that the precursor consists of mature enzyme of 579 amino acids and an N-terminal extension of 56 amino acids. The latter presequence is highly basic in character as found with other mitochondrial preproteins.

摘要

相似文献

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Complete nucleotide sequence of hepatic 5-aminolaevulinate synthase precursor.
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J Bioenerg Biomembr. 1995 Apr;27(2):161-8. doi: 10.1007/BF02110031.
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J Bioenerg Biomembr. 1995 Apr;27(2):151-9. doi: 10.1007/BF02110030.
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