Marco-Fuertes Ana, Vega Santiago, Villora-Gonzalez José, Marin Clara, Montoro-Dasi Laura
Departamento de Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los Alimentos, Facultad de Veterinaria, Instituto de Ciencias Biomédicas, Universidad Cardenal Herrera-CEU, CEU Universities, Calle Santiago Ramón y Cajal 20, 46115 Alfara del Patriarca, Valencia, Spain.
Selvätica Veterinary Clinic, 46020 Valencia, Spain.
Life (Basel). 2024 Jan 24;14(2):170. doi: 10.3390/life14020170.
Companion animal ownership has evolved to new exotic animals, including small mammals, posing a new public health challenge, especially due to the ability of some of these new species to harbour zoonotic bacteria, such as , and spread their antimicrobial resistances (AMR) to other bacteria through the environment they share. Therefore, the objective of the present pilot study was to evaluate the current epidemiological AMR situation in commensal and spp., in non-traditional companion animal small mammals in the Valencia region. For this purpose, 72 rectal swabs of nine different species of small mammals were taken to assess the antimicrobial susceptibility against 28 antibiotics. A total of one serovar Telelkebir 13,23:d:e,n,z and twenty commensal strains were isolated. For strains, a high prevalence of AMR (85%) and MDR (82.6%) was observed, although neither of them had access outside the household. The highest AMR were observed in quinolones, one of the highest priority critically important antimicrobials (HPCIAs) in human medicine. However, no AMR were found for . In conclusion, the results showed that small mammals' commensal poses a public health risk due to the high AMR found, and the ability of this bacterium to transmit its resistance genes to other bacteria. For this reason, this pilot study highlighted the need to establish programmes to control AMR trends in the growing population of new companion animals, as they could disseminate AMR to humans and animals through their shared environment.
伴侣动物的种类已发展到包括小型哺乳动物在内的新奇物种，这带来了新的公共卫生挑战，特别是因为其中一些新物种能够携带人畜共患病菌，如 ，并通过它们共享的环境将其抗菌素耐药性（AMR）传播给其他细菌。因此，本初步研究的目的是评估巴伦西亚地区非传统伴侣动物小型哺乳动物中共生 和 物种目前的AMR流行病学情况。为此，采集了9种不同小型哺乳动物的72份直肠拭子，以评估对28种抗生素的抗菌敏感性。总共分离出一株血清型Telelkebir 13,23:d:e,n,z和20株共生 菌株。对于 菌株，观察到AMR（85%）和多重耐药（MDR，82.6%）的高流行率，尽管它们都没有接触过家庭以外的环境。喹诺酮类药物中观察到最高的AMR，喹诺酮类是人类医学中最高优先级的 critically important antimicrobials（HPCIAs）之一。然而，未发现 有AMR。总之，结果表明，小型哺乳动物的共生 由于发现的高AMR以及这种细菌将其耐药基因传播给其他细菌的能力，构成了公共卫生风险。因此，这项初步研究强调需要建立控制新伴侣动物不断增长的种群中AMR趋势的计划，因为它们可能通过共享环境将AMR传播给人类和动物。
