Caneschi Alice, Bardhi Anisa, Barbarossa Andrea, Zaghini Anna
Department of Veterinary Medical Sciences, Alma Mater Studiorum-University of Bologna, Via Tolara di Sopra 50, Ozzano dell'Emilia, 40064 Bologna, Italy.
Antibiotics (Basel). 2023 Mar 1;12(3):487. doi: 10.3390/antibiotics12030487.
As warned by Sir Alexander Fleming in his Nobel Prize address: . Antimicrobial resistance (AMR) has recently increased due to the overuse and misuse of antibiotics, and their use in animals (food-producing and companion) has also resulted in the selection and transmission of resistant bacteria. The epidemiology of resistance is complex, and factors other than the overall quantity of antibiotics consumed may influence it. Nowadays, AMR has a serious impact on society, both economically and in terms of healthcare. This narrative review aimed to provide a scenario of the state of the AMR phenomenon in veterinary medicine related to the use of antibiotics in different animal species; the impact that it can have on animals, as well as humans and the environment, was considered. Providing some particular instances, the authors tried to explain the vastness of the phenomenon of AMR in veterinary medicine due to many and diverse aspects that cannot always be controlled. The veterinarian is the main reference point here and has a high responsibility towards the human-animal-environment triad. Sharing such a burden with human medicine and cooperating together for the same purpose (fighting and containing AMR) represents an effective example of the application of the One Health approach.
正如亚历山大·弗莱明爵士在其诺贝尔奖演讲中所警告的那样：由于抗生素的过度使用和滥用，抗菌药物耐药性（AMR）最近有所增加，而且抗生素在动物（食用动物和伴侣动物）中的使用也导致了耐药菌的选择和传播。耐药性的流行病学很复杂，除了抗生素的总体消费量之外，其他因素也可能对其产生影响。如今，AMR在经济和医疗保健方面都对社会产生了严重影响。这篇叙述性综述旨在呈现与不同动物物种使用抗生素相关的兽医学中AMR现象的现状；同时考虑了其对动物、人类以及环境可能产生的影响。通过列举一些具体事例，作者试图解释兽医学中AMR现象的广泛性，这是由许多不同方面导致的，而这些方面往往难以完全控制。兽医在此处是主要的参考点，对人类 - 动物 - 环境三元组负有重大责任。与人类医学分担这一负担并为同一目标（对抗和控制AMR）共同合作，是“同一健康”方法应用的一个有效范例。
