The Interaction between Hypovirulence-Associated Chrysoviruses and Their Host Species.

Chrysoviruses are isometric virus particles (35-50 nm in diameter) with a genome composed of double-stranded RNAs (dsRNA). These viruses belonged to the family, named after the first member isolated from . Phylogenetic classification has divided the chrysoviruses into and genera. Currently, these chrysoviruses have been found to infect many fungi, including species, and cause changes in the phenotype and decline in the pathogenicity of the host. Thus, it is a microbial resource with great biocontrol potential against species, causing destructive plant diseases and substantial economic losses. This review provides a comprehensive overview of three chrysovirus isolates (Fusarium graminearum virus 2 (FgV2), Fusarium graminearum virus-ch9 (FgV-ch9), and Fusarium oxysporum f. sp. dianthi mycovirus 1 (FodV1)) reported to decline the pathogenicity of hosts. It also summarizes the recent studies on host response regulation, host RNA interference, and chrysovirus transmission. The information provided in the review will be a reference for analyzing the interaction of species with chrysovirus and proposing opportunities for research on the biocontrol of diseases. Finally, we present reasons for conducting further studies on exploring the interaction between chrysoviruses and and improving the accumulation and transmission efficiency of these chrysoviruses.