Pariente E A, Chaumette M T, Maître F, Delchier J C, Soulé J C, Bader J P
Gastroenterol Clin Biol. 1985 Oct;9(10):738-41.
In a 37-year-old woman with chronic watery diarrhea of three years duration, the diagnostic of collagenous colitis was established by optical and ultrastructural examination of rectal and colonic biopsies. No other cause of diarrhea could be found. Moreover, this patient had also selective IgA deficiency, Grave's disease and chronic atrophic gastritis of auto-immune type. Sequential treatments with loperamide, cholestyramine and antibiotics did not modified diarrhea which improved with salazosulfapyridine and betamethasone enemas. These observations suggest that collagenous colitis might be a part of the spectrum of enteropathies associated with immunoglobulin deficiencies.
在一名患有持续三年慢性水样腹泻的37岁女性中，通过直肠和结肠活检的光学及超微结构检查确诊为胶原性结肠炎。未发现其他腹泻原因。此外，该患者还患有选择性IgA缺乏症、格雷夫斯病和自身免疫型慢性萎缩性胃炎。使用洛哌丁胺、考来烯胺和抗生素的序贯治疗未能改善腹泻，而柳氮磺胺吡啶和倍他米松灌肠剂使腹泻得到改善。这些观察结果表明，胶原性结肠炎可能是与免疫球蛋白缺乏相关的肠病谱的一部分。
