Wilton J H, Hokanson G C, French J C
J Antibiot (Tokyo). 1985 Nov;38(11):1449-52. doi: 10.7164/antibiotics.38.1449.
The isolation and properties of PD 118,576, a new cytotoxic antibiotic obtained from the culture broth of a Streptomyces sp., are described. The structure of this compound was established by spectral analyses of the parent compound and its tri-O-acetyl derivative. PD 118,576 proved to be related to the bafilomycins and therefore is a new member of this recently discovered family of macrolide antibiotics.
