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Siderophores mediate antibiotic resistance.

作者信息

Khan Fabiha Zaheen, Palmer Kelli, Dillon Nicholas

机构信息

Department of Biological Sciences, University of Texas at Dallas, Richardson, TX, USA.

出版信息

Nat Microbiol. 2024 Mar;9(3):587-588. doi: 10.1038/s41564-024-01624-x.

DOI:10.1038/s41564-024-01624-x
PMID:38413833
Abstract
摘要

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Nat Microbiol. 2024 Mar;9(3):587-588. doi: 10.1038/s41564-024-01624-x.
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Siderophore-Antibiotic Conjugate Design: New Drugs for Bad Bugs?铁载体-抗生素缀合物设计:针对坏菌的新药?
Molecules. 2019 Sep 11;24(18):3314. doi: 10.3390/molecules24183314.
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Catecholate siderophore receptor CirA impacts cefiderocol susceptibility in Klebsiella pneumoniae.儿茶酚盐铁载体受体CirA影响肺炎克雷伯菌对头孢地尔的敏感性。
Int J Antimicrob Agents. 2022 Oct;60(4):106646. doi: 10.1016/j.ijantimicag.2022.106646. Epub 2022 Jul 31.
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Hydroxamate siderophores: Natural occurrence, chemical synthesis, iron binding affinity and use as Trojan horses against pathogens.异羟肟酸类铁载体:天然存在、化学合成、铁结合亲和力以及作为对抗病原体的特洛伊木马的用途。
Eur J Med Chem. 2020 Dec 15;208:112791. doi: 10.1016/j.ejmech.2020.112791. Epub 2020 Sep 5.
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Chemistry and Biology of Siderophores from Marine Microbes.海洋微生物中铁载体的化学与生物学
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Characterization of microbial siderophores by mass spectrometry.通过质谱法对微生物铁载体进行表征
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Growth of Actinobacillus pleuropneumoniae is promoted by exogenous hydroxamate and catechol siderophores.外源异羟肟酸和儿茶酚铁载体可促进胸膜肺炎放线杆菌的生长。
Appl Environ Microbiol. 1996 Mar;62(3):853-9. doi: 10.1128/aem.62.3.853-859.1996.
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Potentiation of antibacterial activity of the MB-1 siderophore-monobactam conjugate using an efflux pump inhibitor.使用外排泵抑制剂增强MB-1铁载体-单环β-内酰胺缀合物的抗菌活性。
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Eur J Med Chem. 2019 Nov 15;182:111615. doi: 10.1016/j.ejmech.2019.111615. Epub 2019 Aug 12.

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Meta-Transcriptomic Response to Copper Corrosion in Drinking Water Biofilms.饮用水生物膜对铜腐蚀的宏转录组学响应
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Secondary Metabolites from spp. probiotics as potential treatments for multidrug-resistant pathogens: A comprehensive review.来自益生菌的次生代谢产物作为多重耐药病原体的潜在治疗方法:综述。 (注:原文中“spp.”表述有误,正确可能是“species”等词,推测这里想表达来自某些种类益生菌)
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本文引用的文献

1
Siderophores promote cooperative interspecies and intraspecies cross-protection against antibiotics in vitro.铁载体促进体外物种间和种内抗生素的协同交叉保护。
Nat Microbiol. 2024 Mar;9(3):631-646. doi: 10.1038/s41564-024-01601-4. Epub 2024 Feb 26.
2
Cefiderocol: Systematic Review of Mechanisms of Resistance, Heteroresistance and In Vivo Emergence of Resistance.头孢地尔:耐药机制、异质性耐药及体内耐药性产生的系统评价
Antibiotics (Basel). 2022 May 27;11(6):723. doi: 10.3390/antibiotics11060723.
3
Bicarbonate modulates delafloxacin activity against MDR Staphylococcus aureus and Pseudomonas aeruginosa.
利用环境监测和宏基因组学对津巴布韦哈拉雷的肠道病原体进行特征分析。
J Water Health. 2025 Apr;23(4):477-492. doi: 10.2166/wh.2025.333. Epub 2025 Feb 21.
碳酸氢盐调节德拉沙星对耐多药金黄色葡萄球菌和铜绿假单胞菌的活性。
J Antimicrob Chemother. 2022 Feb 2;77(2):433-442. doi: 10.1093/jac/dkab421.
4
Efficacy and safety of cefiderocol or best available therapy for the treatment of serious infections caused by carbapenem-resistant Gram-negative bacteria (CREDIBLE-CR): a randomised, open-label, multicentre, pathogen-focused, descriptive, phase 3 trial.头孢地尔罗或最佳现有治疗方案治疗碳青霉烯类耐药革兰氏阴性菌引起的严重感染的疗效和安全性(CREDIBLE-CR):一项随机、开放标签、多中心、以病原体为重点、描述性的 3 期临床试验。
Lancet Infect Dis. 2021 Feb;21(2):226-240. doi: 10.1016/S1473-3099(20)30796-9. Epub 2020 Oct 12.
5
Risk Factors for Mortality among Patients with Bloodstream Infections: What Is the Influence of XDR Phenotype on Outcomes?血流感染患者死亡的危险因素:广泛耐药表型对结局有何影响?
J Clin Med. 2020 Feb 14;9(2):514. doi: 10.3390/jcm9020514.
6
Surprising synergy of dual translation inhibition vs. Acinetobacter baumannii and other multidrug-resistant bacterial pathogens.双重翻译抑制对抗鲍曼不动杆菌和其他多药耐药细菌病原体的惊人协同作用。
EBioMedicine. 2019 Aug;46:193-201. doi: 10.1016/j.ebiom.2019.07.041. Epub 2019 Jul 25.
7
Emergence of antibiotic resistance in intensive care unit; a critical review.重症监护病房中抗生素耐药性的出现;一项批判性综述。
Genes Dis. 2019 Apr 17;6(2):109-119. doi: 10.1016/j.gendis.2019.04.001. eCollection 2019 Jun.
8
Evaluation of the in vitro growth of urinary tract infection-causing gram-negative and gram-positive bacteria in a proposed synthetic human urine (SHU) medium.在一种拟议的合成人尿(SHU)培养基中对引起尿路感染的革兰氏阴性菌和革兰氏阳性菌进行体外生长评估。
J Microbiol Methods. 2016 Aug;127:164-171. doi: 10.1016/j.mimet.2016.06.013. Epub 2016 Jun 14.
9
Essential genome of Pseudomonas aeruginosa in cystic fibrosis sputum.囊性纤维化痰液中铜绿假单胞菌的必需基因组
Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):4110-5. doi: 10.1073/pnas.1419677112. Epub 2015 Mar 16.