Biomedical Physics Department, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
General Electric HealthCare, Riyadh, Saudi Arabia.
J Appl Clin Med Phys. 2024 Apr;25(4):e14315. doi: 10.1002/acm2.14315. Epub 2024 Feb 28.
To report on the performance characteristics of the 5-ring GE Discovery MI PET/CT systems using the AAPM TG-126 report and compare these results to NEMA NU 2-2012 where applicable.
TG-126 testing was performed on two GE 5-Rings Discovery MI scanners. Tests performed included spatial resolution, PET/CT image-registration accuracy, sensitivity, count rate performance, accuracy of corrections, image contrast, scatter/attenuation correction, and image uniformity. All acquired data were analyzed using scanner console or free software tools as described by TG-126 and the results were then compared to published NEMA NU 2-2012 values.
Both scanners gave similar resolution results for TG-126 and NEMA NU 2-2012 and were within manufacturer specifications. Image-registration accuracy between PET and CT using our clinical protocol showed excellent results with values ≤1 mm. Sensitivity using TG-126 was 19.43 cps/kBq while for NEMA the value was 20.73 cps/kBq. The peak noise-equivalent counting rate was 2174 kcps at 63.1 kBq/mL and is not comparable to NEMA NU 2-2012 due to differences in phantoms and methods used to measure and calculate this parameter. The accuracy of corrections for count losses for TG-126 were expressed in SUV values and found to be within 10% of the expected SUV measurement of 1. Image contrast and scatter/attenuation correction using the TG-126 method gave acceptable results. Image uniformity assessment resulted in values within the recommended ± 5% limits.
These results show that the 5-ring GE Discovery MI PET/CT scanner testing using TG-126 is reproducible and has similar results to NEMA NU 2-2012 tests where applicable. We hope these results start to form the basis to compare PET/CT systems using TG-126.
根据 AAPM TG-126 报告报告五环 GE Discovery MI PET/CT 系统的性能特征,并在适用的情况下将这些结果与 NEMA NU 2-2012 进行比较。
对两台 GE 五环 Discovery MI 扫描仪进行 TG-126 测试。进行的测试包括空间分辨率、PET/CT 图像配准精度、灵敏度、计数率性能、校正精度、图像对比度、散射/衰减校正和图像均匀性。所有采集的数据均使用 TG-126 中描述的扫描仪控制台或免费软件工具进行分析,然后将结果与已发布的 NEMA NU 2-2012 值进行比较。
两台扫描仪在 TG-126 和 NEMA NU 2-2012 中的分辨率结果相似,均在制造商规格范围内。使用我们的临床方案,PET 和 CT 之间的图像配准精度显示出出色的结果,值≤1mm。使用 TG-126 的灵敏度为 19.43cps/kBq,而 NEMA 的值为 20.73cps/kBq。在 63.1 kBq/mL 时,峰值噪声等效计数率为 2174 kcps,由于使用的体模和测量计算此参数的方法不同,与 NEMA NU 2-2012 不具有可比性。用于计数损失校正的 TG-126 准确性以 SUV 值表示,发现与 1 的预期 SUV 测量值相差在 10%以内。使用 TG-126 方法的图像对比度和散射/衰减校正得到了可接受的结果。图像均匀性评估的结果在推荐的±5%范围内。
这些结果表明,使用 TG-126 对五环 GE Discovery MI PET/CT 扫描仪进行的测试是可重复的,并且在适用的情况下与 NEMA NU 2-2012 测试具有相似的结果。我们希望这些结果能够为使用 TG-126 比较 PET/CT 系统奠定基础。