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24 个西欧国家 1990-2019 年青少年和青年人群 1 型和 2 型糖尿病负担:来自 2019 年全球疾病负担研究的结果。

The Burden of Type 1 and Type 2 Diabetes Among Adolescents and Young Adults in 24 Western European Countries, 1990-2019: Results From the Global Burden of Disease Study 2019.

机构信息

Division of Tropical and Humanitarian Medicine, University of Geneva, Geneva, Switzerland.

Department of Cardiovascular, Endocrine-Metabolic Diseases and Aging, Istituto Superiore di Sanità, Rome, Italy.

出版信息

Int J Public Health. 2024 Feb 14;68:1606491. doi: 10.3389/ijph.2023.1606491. eCollection 2023.

Abstract

As little is known about the burden of type 1 (T1DM) and type 2 diabetes (T2DM) in adolescents in Western Europe (WE), we aimed to explore their epidemiology among 10-24 year-olds. Estimates were retrieved from the Global Burden of Diseases Study (GBD) 2019. We reported counts, rates per 100,000 population, and percentage changes from 1990 to 2019 for prevalence, incidence and years lived with disability (YLDs) of T1DM and T2DM, and the burden of T2DM in YLDs attributable to high body mass index (HBMI), for 24 WE countries. In 2019, prevalence and disability estimates were higher for T1DM than T2DM among 10-24 years old adolescents in WE. However, T2DM showed a greater increase in prevalence and disability than T1DM in the 30 years observation period in all WE countries. Prevalence increased with age, while only minor differences were observed between sexes. Our findings highlight the substantial burden posed by DM in WE among adolescents. Health system responses are needed for transition services, data collection systems, education, and obesity prevention.

摘要

由于对西欧青少年 1 型糖尿病 (T1DM) 和 2 型糖尿病 (T2DM) 的负担知之甚少,我们旨在探讨 10-24 岁青少年的流行病学情况。 估计数取自 2019 年全球疾病负担研究 (GBD)。我们报告了 24 个西欧国家 T1DM 和 T2DM 的患病率、每 10 万人发病率和残疾调整生命年 (YLDs) 的变化百分比,以及归因于高体重指数 (HBMI) 的 T2DM 在 YLDs 中的负担,报告内容为 1990 年至 2019 年的患病率、发病率和 YLDs。 2019 年,在西欧 10-24 岁青少年中,T1DM 的患病率和残疾估计值高于 T2DM。然而,在所有西欧国家的 30 年观察期间,T2DM 的患病率和残疾增长率均高于 T1DM。患病率随年龄增长而增加,而性别之间仅观察到微小差异。 我们的研究结果强调了 DM 在西欧青少年中的巨大负担。需要针对过渡服务、数据收集系统、教育和肥胖预防制定卫生系统应对措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e08/10899430/13cb78769385/ijph-68-1606491-g001.jpg

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