Guo Zhifeng, Ji Wangquan, Yan Mengqing, Zou Xianan, Chen Teng, Bai Fanghui, Wu Yu, Guo Zhe, Song Linlin
Nanyang Maternal and Child Health Care Hospital, Nanyang Central Hospital, Nanyang, China.
College of Public Health, Zhengzhou University, Zhengzhou, China.
Front Glob Womens Health. 2025 Jul 15;6:1528661. doi: 10.3389/fgwh.2025.1528661. eCollection 2025.
Diabetes may have long-term adverse health effects on both women of childbearing age (WCBA) and their future generations. The objective of this study is to provide up-to-date epidemiologic information on the global burden of diabetes in WCBA to inform the development of targeted public health policies.
The data on the burden of diabetes among WCBA from 1990 to 2021 at the global, regional, and national levels were extracted from the Global Burden of Disease 2021 database. The estimated annual percentage change (EAPC) and Bayesian age-period-cohort models were used to assess and predict time burden trends. The slope index and concentration index were used to assess health inequalities associated with the sociodemographic index (SDI).
In 2021, approximately 79.04 million WCBA aged 15-49 years were living with diabetes, resulting in approximately 7.82 million disability-adjusted life years (DALYs). From 1990 to 2021, the age-standardized prevalence rate (ASPR) increased from 1960.8 to 3942.2 per 100,000 WCBA, with an EAPC of 2.25%. The ASPR and age-standardized DALY rate were highest in the low-middle SDI region, at 4,107.0 and 472.3 per 100,000, respectively. DALYs and deaths are concentrated in low SDI countries. By 2040, the global burden of diabetes in WCBA will increase further.
The global burden of diabetes among WCBA has increased over the past three decades. This burden is concentrated in low- and middle-income countries. Diabetes care policies for WCBA urgently need to be improved and popularized.
糖尿病可能对育龄妇女及其后代产生长期不良健康影响。本研究的目的是提供关于育龄妇女糖尿病全球负担的最新流行病学信息，以为制定有针对性的公共卫生政策提供依据。
从《2021年全球疾病负担》数据库中提取1990年至2021年全球、区域和国家层面育龄妇女糖尿病负担的数据。使用估计年度百分比变化（EAPC）和贝叶斯年龄-时期-队列模型来评估和预测时间负担趋势。斜率指数和集中指数用于评估与社会人口指数（SDI）相关的健康不平等。
2021年，约7904万年龄在15至49岁的育龄妇女患有糖尿病，导致约782万伤残调整生命年（DALYs）。1990年至2021年，年龄标准化患病率（ASPR）从每10万育龄妇女1960.8例增加到3942.2例，EAPC为2.25%。低中SDI地区的ASPR和年龄标准化DALY率最高，分别为每10万4107.0例和472.3例。DALYs和死亡集中在低SDI国家。到2040年，育龄妇女糖尿病的全球负担将进一步增加。
在过去三十年中，育龄妇女糖尿病的全球负担有所增加。这一负担集中在低收入和中等收入国家。迫切需要改进和推广针对育龄妇女的糖尿病护理政策。
