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在接受全髋关节置换术的患者中,与肥胖症 III 级患者相比,既往接受过减重手术的患者在 10 年内的翻修率没有差异:倾向匹配分析。

No Difference in Revision Rates up to 10 years Following Total Hip Arthroplasty in Patients Who Had Prior Bariatric Surgery When Compared to Patients Who Had Class III Obesity: A Propensity Matched Analysis.

机构信息

Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Orthopaedic Surgery, University of Washington School of Medicine, Seattle, Washington.

Department of Orthopaedic Surgery, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia.

出版信息

J Arthroplasty. 2024 Jun;39(6):1399-1403.e1. doi: 10.1016/j.arth.2024.02.065. Epub 2024 Feb 27.

DOI:10.1016/j.arth.2024.02.065
PMID:38423258
Abstract

BACKGROUND

There is no clear research showcasing bariatric surgery's (BS's) impact on long-term surgical complications following total hip arthroplasty (THA). Therefore, this study compared the 10-year cumulative incidence and risk of revision following THA in patients who underwent BS when compared to the general population and class III obesity patients who did not undergo BS.

METHODS

Patients who underwent elective THA from 2010 to 2021 were identified using an all-payer claims database. Patients who underwent BS prior to THA were separately matched to a control of the general population and those who had class III obesity (body mass index ≥40) by age, sex, Charlson Comorbidity Index, and diabetes using a 1:4 ratio. Kaplan-Meier analyses generated 10-year cumulative incidence rates, and a Cox proportional hazard ratio (HR) model generated HRs and 95% confidence intervals (CIs).

RESULTS

When compared to the general control, patients who have a history of BS had an elevated 10-year risk of all-cause revision (HR 1.31, 95% CI: 1.16 to 1.47, P < .001), prosthetic joint infection (HR: 1.62, CI: 1.30 to 2.04; P < .001), mechanical loosening (HR: 1.20, CI: 1.01 to 1.44; P = .040), and dislocation/instability (HR: 1.35, CI: 1.09 to 1.68; P = .007). There was no difference in the 10-year risk of all-cause revision or other indications for revision in the BS cohort compared to the matched class III obesity cohort (P = .142).

CONCLUSIONS

Those who underwent BS before THA had comparable 10-year revision rates when compared to those who had class III obesity and higher rates compared to the general population. This suggests BS may not reduce the 10-year surgical risks associated with obesity when compared to a class III obese surgical population.

摘要

背景

目前尚无研究明确展示减重手术(BS)对全髋关节置换术(THA)后长期手术并发症的影响。因此,本研究比较了 BS 组和未行 BS 的普通人群及 III 类肥胖患者(BMI≥40)在 THA 后 10 年的累积翻修发生率和风险。

方法

使用全支付者索赔数据库确定了 2010 年至 2021 年期间接受择期 THA 的患者。对术前接受 BS 的患者,通过年龄、性别、Charlson 合并症指数和糖尿病,按照 1:4 的比例,分别与普通人群和 III 类肥胖患者(BMI≥40)的对照组进行配对。Kaplan-Meier 分析生成 10 年累积发生率,Cox 比例风险比(HR)模型生成 HR 和 95%置信区间(CI)。

结果

与普通对照组相比,有 BS 病史的患者 10 年全因翻修风险升高(HR 1.31,95%CI:1.16 至 1.47,P<.001)、假体关节感染(HR:1.62,CI:1.30 至 2.04;P<.001)、机械松动(HR:1.20,CI:1.01 至 1.44;P=0.040)和脱位/不稳定(HR:1.35,CI:1.09 至 1.68;P=0.007)。BS 组与匹配的 III 类肥胖组在 10 年全因翻修或其他翻修指征的风险方面无差异(P=0.142)。

结论

与 III 类肥胖患者相比,BS 组的 10 年翻修率相当,而与普通人群相比,BS 组的翻修率更高。这表明与 III 类肥胖手术人群相比,BS 可能无法降低肥胖相关的 10 年手术风险。

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