Leicester Real World Evidence Unit, Leicester Diabetes Centre, Department of Population Health Sciences, University of Leicester, Leicester, UK.
Data and Analysis for Social Care and Health Division, Office for National Statistics, Newport, UK.
Eur J Public Health. 2024 Jun 7;34(3):489-496. doi: 10.1093/eurpub/ckae034.
Evidence on the long-term employment consequences of SARS-CoV-2 infection is lacking. We used data from a large, community-based sample in the UK to estimate associations between Long Covid and employment outcomes.
This was an observational, longitudinal study using a pre-post design. We included survey participants from 3 February 2021 to 30 September 2022 when they were aged 16-64 years and not in education. Using conditional logit modelling, we explored the time-varying relationship between Long Covid status ≥12 weeks after a first test-confirmed SARS-CoV-2 infection (reference: pre-infection) and labour market inactivity (neither working nor looking for work) or workplace absence lasting ≥4 weeks.
Of 206 299 participants (mean age 45 years, 54% female, 92% white), 15% were ever labour market inactive and 10% were ever long-term absent during follow-up. Compared with pre-infection, inactivity was higher in participants reporting Long Covid 30 to <40 weeks [adjusted odds ratio (aOR): 1.45; 95% CI: 1.17-1.81] or 40 to <52 weeks (aOR: 1.34; 95% CI: 1.05-1.72) post-infection. Combining with official statistics on Long Covid prevalence, and assuming a correct statistical model, our estimates translate to 27 000 (95% CI: 6000-47 000) working-age adults in the UK being inactive because of Long Covid in July 2022.
Long Covid is likely to have contributed to reduced participation in the UK labour market, though it is unlikely to be the sole driver. Further research is required to quantify the contribution of other factors, such as indirect health effects of the pandemic.
目前缺乏关于 SARS-CoV-2 感染长期就业后果的证据。我们使用来自英国大型社区样本的数据,估计长期新冠病毒感染与就业结果之间的关联。
这是一项使用前后设计的观察性纵向研究。我们纳入了 2021 年 2 月 3 日至 2022 年 9 月 30 日期间年龄在 16-64 岁且未接受教育的调查参与者。使用条件逻辑回归模型,我们探索了在首次经检测确认的 SARS-CoV-2 感染后 12 周及以上的长期新冠病毒感染状况(参考:感染前)与劳动力市场非活跃(既不工作也不寻找工作)或持续≥4 周的工作场所缺勤之间的时变关系。
在 206299 名参与者中(平均年龄 45 岁,54%为女性,92%为白人),15%曾劳动力市场非活跃,10%在随访期间曾长期缺勤。与感染前相比,报告感染后 30-<40 周(调整后的优势比[aOR]:1.45;95%置信区间[CI]:1.17-1.81)或 40-<52 周(aOR:1.34;95% CI:1.05-1.72)的参与者,非活跃的比例更高。结合英国长期新冠病毒感染的官方统计数据,并假设正确的统计模型,我们的估计表明,2022 年 7 月,英国约有 27000 名(95% CI:6000-47000)处于工作年龄的成年人因长期新冠病毒感染而无法工作。
长期新冠病毒感染可能导致英国劳动力市场参与度下降,但不太可能是唯一的驱动因素。需要进一步研究来量化其他因素的贡献,例如大流行对健康的间接影响。