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长期新冠的诊断与治疗挑战

Challenges in diagnosis and treatment of long COVID.

作者信息

Gu Lei, Yue Jian, Lin Jing, Liu Zeyi, Huang Jian-An

机构信息

Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, China.

Institute of Respiratory Diseases, Soochow University, Suzhou, China.

出版信息

Front Med (Lausanne). 2025 Aug 21;12:1641411. doi: 10.3389/fmed.2025.1641411. eCollection 2025.

DOI:10.3389/fmed.2025.1641411
PMID:40917843
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12408318/
Abstract

Despite a large population affected by COVID-19, awareness of long COVID among clinicians is surprisingly limited. This has led to delayed or missed diagnoses and, consequently, inappropriate treatments that fail to address patients' specific needs. Our study highlights the gaps in knowledge and the barriers to effective management of long COVID in the healthcare system. Through this work, we aim to bring attention to these critical issues and advocate for urgent action to improve the clinical management of long COVID.

摘要

尽管有大量人群受到新冠病毒病的影响,但临床医生对新冠后遗症的认识却出奇地有限。这导致了诊断延迟或漏诊,进而导致治疗不当,无法满足患者的特殊需求。我们的研究凸显了医疗系统中在新冠后遗症知识方面的差距以及有效管理的障碍。通过这项工作,我们旨在引起对这些关键问题的关注,并倡导采取紧急行动来改善新冠后遗症的临床管理。

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本文引用的文献

1
Mapping brain changes in post-COVID-19 cognitive decline via FDG PET hypometabolism and EEG slowing.通过氟代脱氧葡萄糖正电子发射断层扫描(FDG PET)代谢减退和脑电图(EEG)减慢来描绘新冠病毒感染后认知功能下降中的脑变化。
Sci Rep. 2025 Jul 2;15(1):23141. doi: 10.1038/s41598-025-04815-6.
2
Chinese herbal medicine for dyspnea and persistent symptoms of long COVID: A systematic review and meta-analysis of randomized controlled trials.用于治疗新冠后呼吸困难及持续症状的中草药:一项随机对照试验的系统评价与荟萃分析
J Integr Med. 2025 Mar;23(2):126-137. doi: 10.1016/j.joim.2025.01.001. Epub 2025 Jan 4.
3
Long COVID facts and findings: a large-scale online survey in 74,075 Chinese participants.新冠长期症状的事实与发现:对74075名中国参与者的大规模在线调查
Lancet Reg Health West Pac. 2024 Oct 11;52:101218. doi: 10.1016/j.lanwpc.2024.101218. eCollection 2024 Nov.
4
Prevalence and risk factors for long COVID in China: A systematic review and meta-analysis of observational studies.中国长期新冠的患病率及风险因素:观察性研究的系统评价与荟萃分析
J Infect Public Health. 2025 Mar;18(3):102652. doi: 10.1016/j.jiph.2025.102652. Epub 2025 Jan 4.
5
Long COVID: a clinical update.长新冠:临床更新。
Lancet. 2024 Aug 17;404(10453):707-724. doi: 10.1016/S0140-6736(24)01136-X. Epub 2024 Jul 31.
6
Work ability and return-to-work of patients with post-COVID-19: a systematic review and meta-analysis.新冠康复患者的工作能力和重返工作岗位情况:一项系统评价和荟萃分析。
BMC Public Health. 2024 Jul 7;24(1):1811. doi: 10.1186/s12889-024-19328-6.
7
Post-COVID syndrome prevalence: a systematic review and meta-analysis.新冠后综合征患病率:系统评价和荟萃分析。
BMC Public Health. 2024 Jul 4;24(1):1785. doi: 10.1186/s12889-024-19264-5.
8
Framing Long Covid through Patient activism in the United States: Patient, Provider, Academic, and Policymaker Views.通过美国的患者行动主义来构建长新冠:患者、提供者、学者和政策制定者的观点。
Soc Sci Med. 2024 Jun;350:116901. doi: 10.1016/j.socscimed.2024.116901. Epub 2024 Apr 17.
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Lancet Microbe. 2024 Aug;5(8):100849. doi: 10.1016/S2666-5247(24)00055-7. Epub 2024 Apr 24.
10
Employment outcomes of people with Long Covid symptoms: community-based cohort study.长新冠症状人群的就业结果:基于社区的队列研究。
Eur J Public Health. 2024 Jun 7;34(3):489-496. doi: 10.1093/eurpub/ckae034.