East & North Hertfordshire NHS Trust including Mount Vernon Cancer Centre, Northwood, Middlesex HA6 2RN, United Kingdom.
Leeds Institute of Medical Research at St James's, University of Leeds, St James's University Hospital, Leeds, United Kingdom.
Eur J Cancer. 2024 Jun;204:113927. doi: 10.1016/j.ejca.2024.113927. Epub 2024 Feb 17.
The cancer-specific health-related quality of life (HRQoL) questionnaire of the European Organisation for Research and Treatment of Cancer (EORTC), the EORTC QLQ-C30, is a frequently applied questionnaire to assess cancer patients' self-reported health used as part of research and clinical practice. Normative data obtained from the general population can facilitate the interpretation of these data. Despite its frequent application, no detailed EORTC QLQ-C30 normative data have yet been published for the United Kingdom (UK). This study presents detailed EORTC QLQ-C30 normative data for the United Kingdom overall and by sex and age.
The data are drawn from a larger published, international, cross-sectional online survey. For the recruitment, the sample was stratified by sex (males, females) and age in five age groups with a sample size of n = 100 per subgroup.
A total of N = 1026 UK respondents completed the survey (n = 517 females, n = 509 males). There were no clear subgroup patterns by sex or age; however, older patients tended to show higher (i.e., better) scores in emotional and social functioning; they also reported some of the lowest (i.e., best) scores for symptoms, such as insomnia, appetite loss, diarrhoea, nausea/vomiting or financial difficulties.
This paper provides EORTC QLQ-C30 general population normative data for the UK, further stratified by sex and age. These data will greatly support the interpretation of EORTC QLQ-C30 scale scores obtained from UK cancer patients, and also enable comparison with other detailed national normative datasets collected in the same project, across several other European countries and the US.
欧洲癌症研究与治疗组织(EORTC)的癌症特异性健康相关生活质量(HRQoL)问卷,即 EORTC QLQ-C30,是一种常用于评估癌症患者自我报告健康状况的问卷,常用于研究和临床实践。从一般人群中获得的规范数据可以帮助解释这些数据。尽管该问卷经常被应用,但目前还没有为英国(UK)提供详细的 EORTC QLQ-C30 规范数据。本研究提供了英国总体以及按性别和年龄划分的详细 EORTC QLQ-C30 规范数据。
这些数据来自一项更大规模的、已发表的、国际性的、横断面在线调查。为了招募参与者,该样本按性别(男性、女性)和年龄分为五个年龄组,每个子组的样本量为 n = 100。
共有 1026 名英国受访者完成了调查(n = 517 名女性,n = 509 名男性)。性别或年龄没有明显的分组模式;然而,年龄较大的患者在情感和社会功能方面的得分往往较高(即更好);他们也报告了一些最低(即最佳)的症状得分,如失眠、食欲减退、腹泻、恶心/呕吐或经济困难。
本文提供了英国 EORTC QLQ-C30 一般人群的规范数据,进一步按性别和年龄进行了细分。这些数据将极大地支持对来自英国癌症患者的 EORTC QLQ-C30 量表得分的解释,也能够与在同一项目中收集的来自其他几个欧洲国家和美国的更详细的国家规范数据集进行比较。