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生活方式医学对心脏病、糖尿病和脑血管疾病的前景

Promise of Lifestyle Medicine for Heart Disease, Diabetes Mellitus, and Cerebrovascular Diseases.

作者信息

Pikula Aleksandra, Gulati Mahima, Bonnet Jonathan P, Ibrahim Sarah, Chamoun Svetlana, Freeman Andrew M, Reddy Koushik

机构信息

Department of Medicine, Division of Neurology, University of Toronto, Ontario, Canada.

Jay and Sari Sonshine Centre for Stroke Prevention and Cerebrovascular Brain Health, Univeristy Health Network, Toronto Western Hospital, Toronto, Ontario, Canada.

出版信息

Mayo Clin Proc Innov Qual Outcomes. 2024 Feb 26;8(2):151-165. doi: 10.1016/j.mayocpiqo.2023.11.005. eCollection 2024 Apr.

Abstract

The burden of noncommunicable chronic diseases has relevant and negative consequences to persons, health care systems, and economies worldwide. Chronic diseases are the leading cause of disability and mortality and are responsible for 90% of health care expenditure. The most common chronic diseases are diabetes mellitus (DM), cardiovascular disease, and cerebrovascular disease (stroke and vascular cognitive impairment). Modifiable risk factors (MRFs) for these conditions include hypertension, hyperlipidemia, smoking, poor diet, and low-physical activity; with hypertension being the most prevalent MRF. Most MRFs can be successfully targeted through lifestyle medicine (LSM), which is a medical specialty that addresses the root causes of chronic diseases through its primary, secondary, and tertiary preventative approaches. Lifestyle medicine comprises 6 pillars (nutrition, physical activity, sleep health, stress reduction, social connections, and substance use) which through various behavioral approaches, focus on regular physical activity, healthy eating, good quality and quantity sleep, and meaningful social connections coupled with the reduction of stress and substance use. This paper will briefly review the evidence and promise of individual LSM pillars in addressing the underlying MRFs of DM, cardiovascular and cerebrovascular disease (specifically stroke and vascular cognitive impairment). Lifestyle medicine holds a great promise for comprehensive and much improved population health. However, the adoption of LSM at the societal scale requires a multifaceted approach and widespread integration would galvanize a paradigm shift to prevent, treat or reverse chronic diseases from the root causes and achieve health equity.

摘要

非传染性慢性病的负担对全球范围内的个人、医疗保健系统和经济都产生了相关的负面影响。慢性病是导致残疾和死亡的主要原因,占医疗保健支出的90%。最常见的慢性病是糖尿病(DM)、心血管疾病和脑血管疾病(中风和血管性认知障碍)。这些疾病的可改变风险因素(MRF)包括高血压、高脂血症、吸烟、不良饮食和低体力活动;其中高血压是最普遍的MRF。大多数MRF可以通过生活方式医学(LSM)成功地加以应对,生活方式医学是一门医学专业,通过其一、二、三级预防方法来解决慢性病的根本原因。生活方式医学包括6个支柱(营养、体力活动、睡眠健康、减压、社会联系和物质使用),通过各种行为方式,注重规律的体力活动、健康饮食、高质量和充足的睡眠以及有意义的社会联系,同时减少压力和物质使用。本文将简要回顾生活方式医学各个支柱在应对糖尿病、心血管和脑血管疾病(特别是中风和血管性认知障碍)潜在MRF方面的证据和前景。生活方式医学对全面改善人群健康有着巨大的前景。然而,在社会层面采用生活方式医学需要采取多方面的方法,广泛整合将促使形成一种范式转变,从根本原因预防、治疗或逆转慢性病,并实现健康公平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e54e/10907160/1f844901407b/gr1.jpg

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