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一种使用混合CNN-DenseNet模型对皮肤组织病理学图像进行皮肤病学分类的方法。

An approach to the dermatological classification of histopathological skin images using a hybridized CNN-DenseNet model.

作者信息

De Anubhav, Mishra Nilamadhab, Chang Hsien-Tsung

机构信息

School of Computing Science & Engineering, VIT Bhopal University, Madhya Pradesh, India.

Department of Computer Science and Information Engineering, Chang Gung University, Taoyuan, Taiwan.

出版信息

PeerJ Comput Sci. 2024 Feb 26;10:e1884. doi: 10.7717/peerj-cs.1884. eCollection 2024.

Abstract

This research addresses the challenge of automating skin disease diagnosis using dermatoscopic images. The primary issue lies in accurately classifying pigmented skin lesions, which traditionally rely on manual assessment by dermatologists and are prone to subjectivity and time consumption. By integrating a hybrid CNN-DenseNet model, this study aimed to overcome the complexities of differentiating various skin diseases and automating the diagnostic process effectively. Our methodology involved rigorous data preprocessing, exploratory data analysis, normalization, and label encoding. Techniques such as model hybridization, batch normalization and data fitting were employed to optimize the model architecture and data fitting. Initial iterations of our convolutional neural network (CNN) model achieved an accuracy of 76.22% on the test data and 75.69% on the validation data. Recognizing the need for improvement, the model was hybridized with DenseNet architecture and ResNet architecture was implemented for feature extraction and then further trained on the HAM10000 and PAD-UFES-20 datasets. Overall, our efforts resulted in a hybrid model that demonstrated an impressive accuracy of 95.7% on the HAM10000 dataset and 91.07% on the PAD-UFES-20 dataset. In comparison to recently published works, our model stands out because of its potential to effectively diagnose skin diseases such as melanocytic nevi, melanoma, benign keratosis-like lesions, basal cell carcinoma, actinic keratoses, vascular lesions, and dermatofibroma, all of which rival the diagnostic accuracy of real-world clinical specialists but also offer customization potential for more nuanced clinical uses.

摘要

本研究旨在应对利用皮肤镜图像实现皮肤病诊断自动化的挑战。主要问题在于准确分类色素沉着性皮肤病变,传统上这依赖皮肤科医生的人工评估,容易出现主观性且耗时。通过集成混合卷积神经网络(CNN)-密集连接网络(DenseNet)模型,本研究旨在克服区分各种皮肤病的复杂性并有效实现诊断过程的自动化。我们的方法包括严格的数据预处理、探索性数据分析、归一化和标签编码。采用了模型混合、批量归一化和数据拟合等技术来优化模型架构和数据拟合。我们的卷积神经网络(CNN)模型的初始迭代在测试数据上的准确率为76.22%,在验证数据上的准确率为75.69%。认识到需要改进,该模型与DenseNet架构进行了混合,并采用ResNet架构进行特征提取,然后在HAM10000和PAD-UFES-20数据集上进一步训练。总体而言,我们的努力产生了一个混合模型,该模型在HAM10000数据集上的准确率达到了令人印象深刻的95.7%,在PAD-UFES-20数据集上的准确率为91.07%。与最近发表的研究相比,我们的模型脱颖而出,因为它有潜力有效诊断诸如黑素细胞痣、黑色素瘤、良性角化病样病变、基底细胞癌、光化性角化病、血管病变和皮肤纤维瘤等皮肤病,所有这些皮肤病的诊断准确率都可与现实世界中的临床专家相媲美,而且还为更细致的临床应用提供了定制潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c160/10909212/73ef3446e74f/peerj-cs-10-1884-g001.jpg

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