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姜黄素补充对足球比赛后运动表现和肌肉损伤的影响:一项双盲安慰剂对照交叉研究。

Impact of curcumin supplementation on exercise performance and muscle damage after a soccer match: a double-blind placebo-controlled cross-over study.

机构信息

Department of Sport Research, Japan Institute of Sports Sciences, Tokyo, Japan.

Japan Society for the Promotion of Science, Tokyo, Japan.

出版信息

Eur J Appl Physiol. 2024 Jul;124(7):2161-2170. doi: 10.1007/s00421-024-05429-y. Epub 2024 Mar 4.

DOI:10.1007/s00421-024-05429-y
PMID:38436665
Abstract

PURPOSE

Curcumin ingestion can mitigate muscle damage, soreness, and inflammation following a laboratory-based eccentric exercise. Similar effects were observed in recent field-based studies wherein responses were evaluated after a soccer match. However, various potential confounding factors, such as matching opponent skill levels and daily training conditions, may have influenced the outcomes. In the present study, we investigated whether curcumin intake ameliorates changes in muscle damage markers following a soccer match while controlling for the potential confounding factors.

METHODS

Fifteen collegiate athletes were tested in a randomized, double-blind, cross-over manner. They were recruited from the same college soccer team and thus followed the same daily training regimen and competition levels. Furthermore, athletes positioning during matches were counterbalanced. They consumed either 180 mg/day of curcumin or a placebo starting 1 h before the match and continuing for 2 days after a match (two 45-min plays and a 15-min half-time). Muscle soreness, jump performance (including countermovement jump and rebound jump index), and inflammatory and muscle damage markers (high-sensitive C-reactive protein, serum creatine kinase activity, and urinary N-terminal fragment of titin concentration) were evaluated before and after the match. The washout period between matches was set at 1 week.

RESULTS

After the match, all markers showed similarity between the placebo and curcumin conditions (all P > 0.208).

CONCLUSION

These findings indicate that ingesting 180 mg/day of curcumin may not expedite recovery from muscle damage elicited by soccer matches in collegiate soccer players.

摘要

目的

姜黄素摄入可减轻实验室基础离心运动后肌肉损伤、酸痛和炎症。最近的实地研究也观察到了类似的效果,其中在足球赛后评估了反应。然而,各种潜在的混杂因素,如匹配对手的技能水平和日常训练条件,可能影响了结果。在本研究中,我们调查了在控制潜在混杂因素的情况下,姜黄素摄入是否能改善足球赛后肌肉损伤标志物的变化。

方法

15 名大学生运动员以随机、双盲、交叉方式进行测试。他们来自同一支大学足球队,因此遵循相同的日常训练方案和比赛水平。此外,比赛中运动员的位置是平衡的。他们在比赛前 1 小时开始每天服用 180 毫克姜黄素或安慰剂,持续 2 天(两场 45 分钟的比赛和一场 15 分钟的中场休息)。在比赛前后评估肌肉酸痛、跳跃表现(包括反向跳跃和反弹跳跃指数)、炎症和肌肉损伤标志物(高敏 C 反应蛋白、血清肌酸激酶活性和肌联蛋白 N 端片段浓度)。比赛之间的洗脱期为 1 周。

结果

比赛后,安慰剂和姜黄素条件下所有标志物均相似(均 P>0.208)。

结论

这些发现表明,每天摄入 180 毫克姜黄素可能不会加速大学生足球运动员因足球比赛引起的肌肉损伤的恢复。

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