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人类基因组学研究中的类型学思维助长了科学种族主义的产生和突出。

Typological thinking in human genomics research contributes to the production and prominence of scientific racism.

作者信息

Bird Kevin A, Carlson Jedidiah

机构信息

Department of Plant Sciences, University of California, Davis, CA, United States.

Department of Integrative Biology and Department of Population Health, University of Texas, Austin, TX, United States.

出版信息

Front Genet. 2024 Feb 19;15:1345631. doi: 10.3389/fgene.2024.1345631. eCollection 2024.

DOI:10.3389/fgene.2024.1345631
PMID:38440191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10910073/
Abstract

Public genomic datasets like the 1000 Genomes project (1KGP), Human Genome Diversity Project (HGDP), and the Adolescent Brain Cognitive Development (ABCD) study are valuable public resources that facilitate scientific advancements in biology and enhance the scientific and economic impact of federally funded research projects. Regrettably, these datasets have often been developed and studied in ways that propagate outdated racialized and typological thinking, leading to fallacious reasoning among some readers that social and health disparities among the so-called races are due in part to innate biological differences between them. We highlight how this framing has set the stage for the racist exploitation of these datasets in two ways: First, we discuss the use of public biomedical datasets in studies that claim support for innate genetic differences in intelligence and other social outcomes between the groups identified as races. We further highlight recent instances of this which involve unauthorized access, use, and dissemination of public datasets. Second, we discuss the use of simple figures meant for quick dissemination among lay audiences, of population genetic data to argue for a biological basis for purported human racial groups. We close with recommendations for scientists, to preempt the exploitation and misuse of their data, and for funding agencies, to better enforce violations of data use agreements.

摘要

像千人基因组计划(1KGP)、人类基因组多样性计划(HGDP)以及青少年大脑认知发展(ABCD)研究这样的公共基因组数据集,都是宝贵的公共资源,有助于推动生物学领域的科学进步,并增强联邦资助研究项目的科学和经济影响力。遗憾的是,这些数据集的开发和研究方式往往传播了过时的种族化和类型学思维,导致一些读者产生错误的推理,认为所谓种族之间的社会和健康差异部分归因于它们之间固有的生物学差异。我们强调这种框架如何以两种方式为这些数据集的种族主义利用奠定了基础:第一,我们讨论在一些研究中使用公共生物医学数据集,这些研究声称支持在被认定为种族的群体之间,在智力和其他社会结果方面存在先天性遗传差异。我们进一步强调最近发生的涉及未经授权访问、使用和传播公共数据集的此类事件。第二,我们讨论使用一些简单图表,这些图表旨在向普通受众快速传播群体遗传数据,以论证所谓人类种族群体存在生物学基础。最后,我们为科学家提出建议,以防止其数据被利用和滥用,同时也为资助机构提出建议,以便更好地执行对数据使用协议违规行为的处理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21e9/10910073/d4dc54e860e9/fgene-15-1345631-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21e9/10910073/d4dc54e860e9/fgene-15-1345631-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21e9/10910073/d4dc54e860e9/fgene-15-1345631-g001.jpg

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