Kiran Neelakanta Sarvashiva, Yashaswini Chandrashekar, Singh Sudarshan, Prajapati Bhupendra Gopalbhai
Department of Biotechnology, School of Applied Sciences, REVA University, Bengaluru, Karnataka India.
Office of Research Administration, Chiang Mai University, Chiang Mai, Thailand.
3 Biotech. 2024 Apr;14(4):95. doi: 10.1007/s13205-024-03946-3. Epub 2024 Mar 4.
Microbial exopolysaccharides (EPS) have gained significant attention as versatile biomolecules with multifarious applications across various sectors. This review explores the valorisation of EPS and its potential impact on diverse sectors, including food, pharmaceuticals, cosmetics, and biotechnology. EPS, secreted by microorganisms, possess unique physicochemical properties, such as high molecular weight, water solubility, and biocompatibility, making them attractive for numerous functional roles. Additionally, EPS exhibit significant bioactivity, contributing to their potential use in pharmaceuticals for drug delivery and tissue engineering applications. Moreover, the eco-friendly and sustainable nature of microbial EPS production aligns with the growing demand for environmentally conscious processes. However, challenges still exist in large-scale production, purification, and regulatory approval for commercial use. Advances in bioprocessing and microbial engineering offer promising solutions to overcome these hurdles. Stringent investigations have concluded EPS as novel sources for sustainable applications that are likely to emerge and develop, further reinforcing the significance of these biopolymers in addressing contemporary societal needs and driving innovation in various industrial sectors. Overall, the microbial EPS represents a thriving field with immense potential for meeting diverse industrial demands and advancing sustainable technologies.
微生物胞外多糖（EPS）作为一种具有多种应用的多功能生物分子，已受到广泛关注。本文综述了EPS的价值及其对食品、制药、化妆品和生物技术等不同领域的潜在影响。微生物分泌的EPS具有独特的物理化学性质，如高分子量、水溶性和生物相容性，使其在众多功能角色中具有吸引力。此外，EPS具有显著的生物活性，有助于其在药物递送和组织工程应用中的潜在用途。此外，微生物EPS生产的环保和可持续性质与对环境意识过程的需求不断增长相一致。然而，大规模生产、纯化和商业用途的监管批准仍存在挑战。生物加工和微生物工程的进展为克服这些障碍提供了有希望的解决方案。严格的研究得出结论，EPS是可持续应用的新来源，可能会出现并发展，进一步加强了这些生物聚合物在满足当代社会需求和推动各工业部门创新方面的重要性。总体而言，微生物EPS是一个蓬勃发展的领域，具有满足各种工业需求和推进可持续技术的巨大潜力。
