Salinas Meagen, Yazdani Umar, Oblack Austin, McDaniels Bradley, Ahmed Nida, Haque Bilal, Pouratian Nader, Chitnis Shilpa
Department of Neurology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA.
Neurology Section, VA North Texas Health Care System, Dallas, TX, USA.
Ther Adv Neurol Disord. 2024 Mar 6;17:17562864241233038. doi: 10.1177/17562864241233038. eCollection 2024.
Deep brain stimulation (DBS) is an established therapy for Parkinson's disease (PD) that can significantly improve motor symptoms and quality of life. Despite its effectiveness, little is known about patient perceptions of DBS.
To evaluate patient perceptions of DBS for PD, focusing on understanding, satisfaction, and factors influencing their outlook. This study aims to enhance patient education and counseling by identifying key determinants of patient perceptions.
A patient survey.
We surveyed 77 PD patients who had undergone DBS at multiple centers using a comprehensive questionnaire. The questionnaire included questions on demographic information, disease history, and detailed understanding about the indications for DBS, side effects, outlook, and other common misconceptions. We summarize data using measures of central tendency and dispersion appropriate to the data type (categorical, continuous, proportional) and model relationships among variables using fractional and linear regression methods.
Participants had a median age of 66 years, were predominantly male (66%), Caucasian (90%), well-educated (79% with at least college degrees), and had a disease duration of greater than 5 years (97%). They conveyed good understanding of the signs and symptoms addressed by DBS across the motor and non-motor domains and associated side effects. Regression analysis identified age, disease duration, and education level as key determinants of patient understanding and outlook of DBS.
Our study provides a detailed understanding of patient perceptions of DBS for PD, including the benefits, challenges, and misconceptions. Our findings underscore the importance of identifying the causes of disparities in patient knowledge and perceptions regarding DBS to tailor patient counseling and ensure optimal treatment outcomes.
深部脑刺激（DBS）是一种已确立的帕金森病（PD）治疗方法，可显著改善运动症状和生活质量。尽管其疗效显著，但对于患者对DBS的看法知之甚少。
评估帕金森病患者对DBS的看法，重点关注理解程度、满意度以及影响其看法的因素。本研究旨在通过确定患者看法的关键决定因素来加强患者教育和咨询。
一项患者调查。
我们使用一份综合问卷对多个中心接受过DBS治疗的77名帕金森病患者进行了调查。问卷包括有关人口统计学信息、疾病史以及对DBS适应症、副作用、前景和其他常见误解的详细理解等问题。我们使用适合数据类型（分类、连续、比例）的集中趋势和离散度测量方法汇总数据，并使用分数和线性回归方法对变量之间的关系进行建模。
参与者的年龄中位数为66岁，主要为男性（66%），白种人（90%），受过良好教育（79%至少拥有大学学位），疾病持续时间超过5年（97%）。他们对DBS在运动和非运动领域解决的体征和症状以及相关副作用有较好的理解。回归分析确定年龄、疾病持续时间和教育水平是患者对DBS理解和看法的关键决定因素。
我们的研究详细了解了帕金森病患者对DBS的看法，包括益处、挑战和误解。我们的研究结果强调了确定患者对DBS知识和看法差异原因的重要性，以便为患者提供个性化咨询并确保最佳治疗效果。
