From the Ophthalmic Biophysics Laboratory, L V Prasad Eye Institute, Hyderabad, Telangana, India (Natarajan, Singh, Mohamed, Vadavalli); Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, Florida (Heilman, Ruggeri, Parel, Manns); Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, Florida (Heilman, Ruggeri, Parel, Manns); Brien Holden Vision Institute Limited, Sydney, New South Wales, Australia; School of Optometry and Vision Science, The University of New South Wales, Sydney, New South Wales, Australia (Ho); Cataract & Refractive surgery services, L V Prasad Eye Institute, Hyderabad, Telangana, India (Singh, Reddy, Vadavalli); The Shantilal Shanghvi Cornea Institute, L V Prasad Eye Institute, Hyderabad, Telangana, India (Vadavalli).
J Cataract Refract Surg. 2024 Jun 1;50(6):637-643. doi: 10.1097/j.jcrs.0000000000001441.
To quantify the angular dependence of monofocal intraocular lens (IOL) power.
Ophthalmic Biophysics Laboratory, Kallam Anji Reddy campus, L V Prasad Eye Institute, Hyderabad, India.
Laboratory study.
Experiments were performed on IOLs from 2 different manufacturers (APPALENS 207, Appasamy Associates and SN60WF, Alcon Laboratories, Inc.). IOL powers ranged from 17 to 25 diopters (D). The IOLs were mounted in a fluid-filled chamber, and the on-axis and off-axis powers were measured using a laser ray tracing system over the central 3 mm zone with delivery angles ranging from -30 to +30 degrees in 5-degree increments. The position of the best focus was calculated for each IOL at each angle. The angular dependence of IOL power was compared with theoretical predictions.
Peripheral defocus increased significantly with increasing incidence angle and power. The peripheral defocus at ±30 degrees increased from 5.8 to 8.5 D when the power increased from 17.5 to 24.5 D for APPALENS 207 and from 4.9 to 7.4 D when the power increased from 17 to 25 D for SN60WF. The mean difference between the measured and theoretical tangential power at ±30 degrees was 0.50 ± 0.16 D for the APPALENS 207 and -0.40 ± 0.10 D for the SN60WF, independent of IOL power.
IOLs introduce a significant amount of peripheral defocus which varies significantly with IOL power and design. Given that peripheral defocus is related to lens power, replacement of the crystalline lens (approximately 24 D) with an IOL will produce a significant difference in peripheral defocus profile after surgery.
量化单焦点人工晶状体(IOL)的光角依赖性。
印度海得拉巴 L V 普拉沙德眼科研究所卡兰·安吉·雷迪校区眼科生物物理实验室。
实验室研究。
对来自 2 个不同制造商的 IOL(Appasamy 协会的 APPALENS 207 和 Alcon 实验室的 SN60WF)进行实验。IOL 功率范围为 17 至 25 屈光度(D)。IOL 安装在充满液体的腔室内,使用激光射线跟踪系统在中央 3mm 区域内测量光轴和光轴外的功率,传输角度从-30 度到+30 度,每隔 5 度递增。计算每个 IOL 在每个角度下的最佳焦点位置。将 IOL 功率的角度依赖性与理论预测进行比较。
随着入射角和功率的增加,周边离焦显著增加。当 APPALENS 207 的功率从 17.5D 增加到 24.5D 时,或当 SN60WF 的功率从 17D 增加到 25D 时,在±30 度时的周边离焦从 5.8D 增加到 8.5D。APPALENS 207 在±30 度时测量的和理论的切线功率之间的平均差异为 0.50±0.16D,SN60WF 为-0.40±0.10D,与 IOL 功率无关。
IOL 会引入大量的周边离焦,其随 IOL 功率和设计的变化而显著变化。由于周边离焦与镜片功率有关,用 IOL 替代晶状体(约 24D)会在手术后产生显著不同的周边离焦轮廓。