Department of Pharmacognosy and Biomaterials, Poznan University of Medical Sciences, Rokietnicka 3, 60-806 Poznan, Poland.
Department of Rheumatology, Rehabilitation and Internal Diseases, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
Nutrients. 2024 Mar 5;16(5):741. doi: 10.3390/nu16050741.
The health benefits of ginger rhizomes () have been known for centuries. Recently, ginger root has gained more attention due to its anti-inflammatory and analgesic activities. Many of the bioactive components of ginger may have therapeutic benefits in treating inflammatory arthritis. Their properties seem especially helpful in treating diseases linked to persistent inflammation and pain, symptoms present in the course of the most prevalent rheumatic diseases, such as osteoarthritis (OA) and rheumatoid arthritis (RA). This review analyzes the current knowledge regarding ginger's beneficial anti-inflammatory effect in both in vitro and in vivo studies as well as clinical trials. The drug delivery systems to improve ginger's bioavailability and medicinal properties are discussed. Understanding ginger's beneficial aspects may initiate further studies on improving its bioavailability and therapeutic efficacy and achieving more a comprehensive application in medicine.
姜根茎的健康益处已为人所知数个世纪。最近，由于其抗炎和镇痛活性，姜根受到了更多的关注。姜的许多生物活性成分可能具有治疗炎症性关节炎的益处。它们的特性似乎特别有助于治疗与持续炎症和疼痛相关的疾病，这些症状存在于最常见的风湿性疾病（如骨关节炎（OA）和类风湿关节炎（RA））的过程中。这篇综述分析了目前关于姜在体外和体内研究以及临床试验中有益的抗炎作用的知识。还讨论了改善姜生物利用度和药用特性的药物传递系统。了解姜的有益方面可能会促使进一步研究提高其生物利用度和治疗效果，并在医学中实现更全面的应用。
