Department of Urology, Affiliated Hospital of North Sichuan Medical College, 1 MaoYuan Nan Road, Nanchong, 637000, Sichuan, China.
World J Urol. 2024 Mar 13;42(1):142. doi: 10.1007/s00345-024-04861-1.
In the past, research has shown that a higher body mass index (BMI) is one of the variables that increase the likelihood of kidney stones; however, no studies have found a connection between the two in the type II diabetic population. The purpose of this research is to reveal the association between BMI and kidney stones in the type II diabetic population.
We selected demographic data, laboratory data, lifestyle, and medical history from the NHANES. Specifically includes age, gender, systemic immune-inflammation index (SII), poverty income rate (PIR), body mass index (BMI), kidney stones, education, coronary artery disease, smoking, and drinking.
BMI and kidney stones were shown to have a positive association in type II diabetics (blood sugar level > 7.0 mmol/L or diagnosed by a doctor) (OR = 1.021, 95% CI 1.008-1.033, P = 0.001), even after controlling for factors, such as age, gender, race, education level, coronary heart disease, smoking, and drinking. The subgroup analysis revealed a more significant positive association among the 67-80 years, female and Non-Hispanic White population.
There is a positive correlation between BMI and kidney stones among the type II diabetic population.
过去的研究表明，较高的体重指数（BMI）是增加肾结石可能性的因素之一；然而，在 2 型糖尿病患者群体中，尚未发现两者之间存在关联。本研究旨在揭示 2 型糖尿病患者群体中 BMI 与肾结石之间的关联。
我们从 NHANES 中选择了人口统计学数据、实验室数据、生活方式和病史。具体包括年龄、性别、系统性免疫炎症指数（SII）、贫困收入比（PIR）、体重指数（BMI）、肾结石、教育程度、冠心病、吸烟和饮酒。
研究表明，在 2 型糖尿病患者（血糖水平>7.0mmol/L 或经医生诊断）中，BMI 与肾结石呈正相关（OR=1.021，95%CI 1.008-1.033，P=0.001），即使在控制了年龄、性别、种族、教育程度、冠心病、吸烟和饮酒等因素后也是如此。亚组分析显示，在 67-80 岁、女性和非西班牙裔白人人群中，这种正相关更为显著。
在 2 型糖尿病患者群体中，BMI 与肾结石之间存在正相关关系。
