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糖尿病患者的 BMI 与肾结石之间存在正相关关系:来自 NHANES 的横断面研究。

A positive association between BMI and kidney stones among the diabetic population: a cross-sectional study from NHANES.

机构信息

Department of Urology, Affiliated Hospital of North Sichuan Medical College, 1 MaoYuan Nan Road, Nanchong, 637000, Sichuan, China.

出版信息

World J Urol. 2024 Mar 13;42(1):142. doi: 10.1007/s00345-024-04861-1.


DOI:10.1007/s00345-024-04861-1
PMID:38478086
Abstract

BACKGROUND: In the past, research has shown that a higher body mass index (BMI) is one of the variables that increase the likelihood of kidney stones; however, no studies have found a connection between the two in the type II diabetic population. The purpose of this research is to reveal the association between BMI and kidney stones in the type II diabetic population. METHODS: We selected demographic data, laboratory data, lifestyle, and medical history from the NHANES. Specifically includes age, gender, systemic immune-inflammation index (SII), poverty income rate (PIR), body mass index (BMI), kidney stones, education, coronary artery disease, smoking, and drinking. RESULTS: BMI and kidney stones were shown to have a positive association in type II diabetics (blood sugar level > 7.0 mmol/L or diagnosed by a doctor) (OR = 1.021, 95% CI 1.008-1.033, P = 0.001), even after controlling for factors, such as age, gender, race, education level, coronary heart disease, smoking, and drinking. The subgroup analysis revealed a more significant positive association among the 67-80 years, female and Non-Hispanic White population. CONCLUSIONS: There is a positive correlation between BMI and kidney stones among the type II diabetic population.

摘要

背景:过去的研究表明,较高的体重指数(BMI)是增加肾结石可能性的因素之一;然而,在 2 型糖尿病患者群体中,尚未发现两者之间存在关联。本研究旨在揭示 2 型糖尿病患者群体中 BMI 与肾结石之间的关联。

方法:我们从 NHANES 中选择了人口统计学数据、实验室数据、生活方式和病史。具体包括年龄、性别、系统性免疫炎症指数(SII)、贫困收入比(PIR)、体重指数(BMI)、肾结石、教育程度、冠心病、吸烟和饮酒。

结果:研究表明,在 2 型糖尿病患者(血糖水平>7.0mmol/L 或经医生诊断)中,BMI 与肾结石呈正相关(OR=1.021,95%CI 1.008-1.033,P=0.001),即使在控制了年龄、性别、种族、教育程度、冠心病、吸烟和饮酒等因素后也是如此。亚组分析显示,在 67-80 岁、女性和非西班牙裔白人人群中,这种正相关更为显著。

结论:在 2 型糖尿病患者群体中,BMI 与肾结石之间存在正相关关系。

相似文献

[1]
A positive association between BMI and kidney stones among the diabetic population: a cross-sectional study from NHANES.

World J Urol. 2024-3-13

[2]
Physical Activity Reduces the Effect of High Body Mass Index on Kidney Stones in Diabetes Participants From the 2007-2018 NHANES Cycles: A Cross-Sectional Study.

Front Public Health. 2022

[3]
Systemic immune-inflammation index is associated with diabetic kidney disease in Type 2 diabetes mellitus patients: Evidence from NHANES 2011-2018.

Front Endocrinol (Lausanne). 2022

[4]
Association between cardiometabolic index and kidney stones in US diabetic patients: NHANES 2007-2018.

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[5]
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Ren Fail. 2025-12

[6]
Association between the systemic inflammation response index and kidney stones in US adults: a cross-sectional study based on NHANES 2007-2018.

Urolithiasis. 2024-11-21

[7]
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[8]
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[9]
Relationship Between Body Mass Index and Kidney Stones Based on Dose-Response Analyses Using Restricted Cubic Splines Applied to NHANES 2011-2016 Data.

J Ren Nutr. 2021-5

[10]
Diabetes mediates an inverted L-shaped association between cardiometabolic index and kidney stones: a cross-sectional study from NHANES 2007-2020.

Front Endocrinol (Lausanne). 2025-2-25

引用本文的文献

[1]
Both absolute and relative sugar-sweetened beverage intake are associated with kidney stones in U.S. middle-aged and young adults.

World J Urol. 2025-4-23

[2]
Age-stratified analysis of the BMI-kidney stone relationship: findings from a national cross-sectional study.

Front Med (Lausanne). 2025-2-12

[3]
Associations between the conicity index and kidney stone disease prevalence and mortality in American adults.

Sci Rep. 2025-1-6

[4]
Association between the Fatty Liver Index, Metabolic Dysfunction-Associated Steatotic Liver Disease, and the Risk of Kidney Stones.

Kidney Blood Press Res. 2025

本文引用的文献

[1]
E-cigarette use and prevalence of lung diseases among the U.S. population: a NHANES survey.

J Investig Med. 2023-8

[2]
Sex Differences and the Risk of Kidney Stones.

Semin Nephrol. 2022-3

[3]
Associations of Serum Carotenoids With Risk of Cardiovascular Mortality Among Individuals With Type 2 Diabetes: Results From NHANES.

Diabetes Care. 2022-6-2

[4]
Risk factors for kidney stone disease recurrence: a comprehensive meta-analysis.

BMC Urol. 2022-4-19

[5]
Incidence of Kidney Stones in the United States: The Continuous National Health and Nutrition Examination Survey.

J Urol. 2022-4

[6]
Obesity-related indices and its association with kidney stone disease: a cross-sectional and longitudinal cohort study.

Urolithiasis. 2022-2

[7]
Data mining in clinical big data: the frequently used databases, steps, and methodological models.

Mil Med Res. 2021-8-11

[8]
Association Between Systemic Immune-Inflammation Index and Diabetic Depression.

Clin Interv Aging. 2021

[9]
Do Lifestyle Factors Including Smoking, Alcohol, and Exercise Impact Your Risk of Developing Kidney Stone Disease? Outcomes of a Systematic Review.

J Endourol. 2021-1

[10]
Relationship Between Body Mass Index and Kidney Stones Based on Dose-Response Analyses Using Restricted Cubic Splines Applied to NHANES 2011-2016 Data.

J Ren Nutr. 2021-5

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