利用调节性 T 细胞建立免疫耐受。
Harnessing regulatory T cells to establish immune tolerance.
机构信息
Diabetes Center, University of California San Francisco, San Francisco, CA 94143, USA.
Abata Therapeutics, Boston, MA 02472, USA.
出版信息
Sci Transl Med. 2024 Mar 13;16(738):eadm8859. doi: 10.1126/scitranslmed.adm8859.
PMID:38478632
Abstract
Engineered regulatory T (T) cells have emerged as precision therapeutics aimed at inducing immune tolerance while reducing the risks associated with generalized immunosuppression. This Viewpoint highlights the opportunities and challenges for engineered T cell therapies in treating autoimmune and other inflammatory diseases.
摘要
工程化调节性 T（T）细胞已成为精准治疗的手段，旨在诱导免疫耐受，同时降低与广泛免疫抑制相关的风险。本观点强调了工程化 T 细胞疗法在治疗自身免疫和其他炎症性疾病方面的机遇和挑战。
Zotero 插件