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肯尼亚农村的痴呆症筛查:筛查阳性的患病率和影响。

Dementia Screening in Rural Kenya: The Prevalence and Impact of Screening Positive for Dementia.

机构信息

Africa Mental Health Research and Training Foundation, Nairobi, Kenya.

University of Nairobi, Nairobi, Kenya.

出版信息

Neuroepidemiology. 2024;58(3):174-181. doi: 10.1159/000536012. Epub 2024 Mar 19.

Abstract

INTRODUCTION

In Kenya, there is a lack of data on the number of people with dementia. In this article, we aim to estimate the number of community-dwelling older adults (aged 60 years and above) that are potentially living with dementia in rural Kenya.

METHODS

Recruitment of older adults occurred through adopting a convenience approach based on the catchment areas served by ten trained community health workers. Screening was conducted using the Brief Community Screening Instrument for Dementia (CSI-D), in which prevalence ratios were reported. Regression analyses were run to understand the association between screening outcome and wellbeing, social isolation, and employment status (adjusted for age, sex, literacy, geography, and social status).

RESULTS

Of the 3,546 older adults who were screened for dementia, 652 screened positive (PR = 0.18, 95% CIs: 0.17-0.20). Back estimating screen positives based on established sensitivity and specificity of the tool against a gold standard (clinical diagnosis), yielded a prevalence of 9.4% (0.09, 95% CIs: 0.08-0.11). Screening positive for dementia was associated with poorer quality of life (B = -0.17, p < 0.001) and loneliness (B = 0.28, p < 0.001).

CONCLUSION

There are potentially 258,000 older adults living with dementia in Kenya, who likely have poorer outcomes. We need to encourage a timely diagnosis and develop better ways to support people living with dementia in Kenya and other resource-limited settings.

摘要

简介

在肯尼亚,痴呆症患者的人数数据缺乏。本文旨在估算肯尼亚农村地区社区居住的老年人群(年龄在 60 岁及以上)中潜在患有痴呆症的人数。

方法

通过采用基于十名经过培训的社区卫生工作者服务的集水区的便利方法招募老年人。使用简要社区痴呆症筛查工具(CSI-D)进行筛查,报告患病率比。回归分析用于了解筛查结果与幸福感、社会隔离和就业状况之间的关联(调整年龄、性别、文化程度、地理位置和社会地位)。

结果

在对 3546 名老年人进行痴呆症筛查中,有 652 名筛查阳性(PR = 0.18,95%CI:0.17-0.20)。根据工具对金标准(临床诊断)的既定敏感性和特异性对筛查阳性进行反向估计,得出患病率为 9.4%(0.09,95%CI:0.08-0.11)。痴呆症筛查阳性与较差的生活质量(B = -0.17,p < 0.001)和孤独感(B = 0.28,p < 0.001)相关。

结论

肯尼亚可能有 258000 名老年痴呆症患者,他们的结局可能更差。我们需要鼓励及时诊断,并开发更好的方法来支持肯尼亚和其他资源有限环境中的痴呆症患者。

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