Gray William K, Paddick Stella Maria, Collingwood Cecilia, Kisoli Aloyce, Mbowe Godfrey, Mkenda Sarah, Lissu Carolyn, Rogathi Jane, Kissima John, Walker Richard W, Mushi Declare, Chaote Paul, Ogunniyi Adesola, Dotchin Catherine L
Northumbria Healthcare NHS Foundation Trust, North Tyneside General Hospital, North Shields, Tyne and Wear, UK.
Institute of Neuroscience, Newcastle University, Newcastle Upon Tyne, UK.
Int J Geriatr Psychiatry. 2016 Nov;31(11):1199-1207. doi: 10.1002/gps.4415. Epub 2016 Feb 2.
The dementia diagnosis gap in sub-Saharan Africa (SSA) is large, partly because of difficulties in screening for cognitive impairment in the community. As part of the Identification and Intervention for Dementia in Elderly Africans (IDEA) study, we aimed to validate the IDEA cognitive screen in a community-based sample in rural Tanzania METHODS: Study participants were recruited from people who attended screening days held in villages within the rural Hai district of Tanzania. Criterion validity was assessed against the gold standard clinical dementia diagnosis using DSM-IV criteria. Construct validity was assessed against, age, education, sex and grip strength and instrumental activities of daily living (IADLs). Internal consistency and floor and ceiling effects were also examined.
During community screening, the IDEA cognitive screen had high criterion validity, with an area under the receiver operating characteristic curve of 0.855 (95% CI 0.794 to 0.915). Higher scores on the screen were significantly correlated with lower age, male sex, having attended school, better grip strength and improved performance in activities of daily living. Factor analysis revealed a single factor with an eigenvalue greater than one, although internal consistency was only moderate (Cronbach's alpha = 0.534).
The IDEA cognitive screen had high criterion and construct validity and is suitable for use as a cognitive screening instrument in a community setting in SSA. Only moderate internal consistency may partly reflect the multi-domain nature of dementia as diagnosed clinically. Copyright © 2016 John Wiley & Sons, Ltd.
撒哈拉以南非洲地区(SSA)的痴呆症诊断缺口很大,部分原因是在社区中筛查认知障碍存在困难。作为非洲老年人痴呆症识别与干预(IDEA)研究的一部分,我们旨在在坦桑尼亚农村的一个社区样本中验证IDEA认知筛查工具。方法:研究参与者从参加坦桑尼亚农村海伊区各村筛查日活动的人群中招募。根据使用《精神疾病诊断与统计手册》第四版(DSM-IV)标准的金标准临床痴呆症诊断来评估标准效度。根据年龄、教育程度、性别、握力和日常生活工具性活动(IADL)来评估结构效度。还检查了内部一致性以及地板效应和天花板效应。结果:在社区筛查期间,IDEA认知筛查工具具有较高的标准效度,受试者工作特征曲线下面积为0.855(95%可信区间0.794至0.915)。筛查得分越高与年龄越低、男性、受过教育、握力越好以及日常生活活动表现越好显著相关。因子分析揭示了一个特征值大于1的单一因子,尽管内部一致性仅为中等(克朗巴哈系数α = 0.534)。结论:IDEA认知筛查工具具有较高的标准效度和结构效度,适用于作为SSA社区环境中的认知筛查工具。仅中等的内部一致性可能部分反映了临床诊断的痴呆症的多领域性质。版权所有© 2016约翰·威利父子有限公司。