Li Zhi, Coote Joanna M, Subburaman Swathika, Iacoviello Francesco, Page Kristopher, Alles Erwin J, Prokopovich Polina, Parkin Ivan P, Desjardins Adrien E, Noimark Sacha
Department of Medical Physics and Biomedical Engineering University College London London WC1E 6BT UK.
Wellcome / EPSRC Centre for Interventional and Surgical Sciences University College London London W1W 7TY UK.
Adv Funct Mater. 2023 Dec 8;33(50):2301857. doi: 10.1002/adfm.202301857. Epub 2023 Sep 17.
Smart robotic devices remotely powered by magnetic field have emerged as versatile tools for wide biomedical applications. Soft magnetic elastomer (ME) composite membranes with high flexibility and responsiveness are frequently incorporated to enable local actuation for wireless sensing or cargo delivery. However, the fabrication of thin ME membranes with good control in geometry and uniformity remains challenging, as well as the optimization of their actuating performances under low fields (milli-Tesla). In this work, the development of ME membranes comprising of low-cost magnetic powder and highly soft elastomer through a simple template-assisted doctor blading approach, is reported. The fabricated ME membranes are controllable in size (up to centimetre-scale), thickness (tens of microns) and high particle loading (up to 70 wt.%). Conflicting trade-off effects of particle concentration upon magnetic responsiveness and mechanical stiffness are investigated and found to be balanced off as it exceeds 60 wt.%. A highly sensitive fibre-optic interferometric sensing system and a customized fibre-ferrule-membrane probe are first proposed to enable dynamic actuation and real-time displacement characterization. Free-standing ME membranes are magnetically excited under low field down to 2 mT, and optically monitored with nanometer accuracy. The fast and consistent responses of ME membranes showcase their promising biomedical applications in nanoscale actuation and sensing.
由磁场远程供电的智能机器人设备已成为广泛生物医学应用的多功能工具。具有高柔韧性和响应性的软磁弹性体(ME)复合膜经常被用于实现无线传感或货物输送的局部驱动。然而,制造具有良好几何形状和均匀性控制的薄ME膜仍然具有挑战性,以及在低场(毫特斯拉)下优化其驱动性能也很困难。在这项工作中,报告了通过一种简单的模板辅助刮刀法开发由低成本磁性粉末和高柔软度弹性体制成的ME膜。所制造的ME膜在尺寸(可达厘米级)、厚度(几十微米)和高颗粒负载(高达70 wt.%)方面是可控的。研究了颗粒浓度对磁响应性和机械刚度的相互矛盾的权衡效应,发现当颗粒浓度超过60 wt.%时,这种权衡效应会达到平衡。首次提出了一种高灵敏度的光纤干涉传感系统和一种定制的光纤插芯 - 膜探头,以实现动态驱动和实时位移表征。独立的ME膜在低至2 mT的低场下受到磁激发,并以纳米精度进行光学监测。ME膜快速且一致的响应展示了它们在纳米级驱动和传感方面具有广阔前景的生物医学应用。