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用于解析细胞异质性的定量方法——从单细胞到空间组学方法

: Quantitative methods to decipher cellular heterogeneity - from single-cell to spatial omic methods.

作者信息

Chen Xi, Wu Angela Ruohao

机构信息

Department of Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, China.

Division of Life Science, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong S.A.R China.

出版信息

Biophys Rev. 2024 Jan 30;16(1):11-12. doi: 10.1007/s12551-024-01180-y. eCollection 2024 Feb.

Abstract

In this mini-issue, we have a collection of eight reviews that discuss various advanced topics on the investigation of cellular heterogeneity. These reviews highlight the latest developments in technologies that capture and assess biology at single cell resolution, as well as approaches for cellular measurements with spatial information. Challenges and opportunities to develop future innovations and approaches are also presented.

摘要

在本期特刊中,我们收集了八篇综述,讨论了细胞异质性研究中的各种前沿话题。这些综述突出了在单细胞分辨率下捕获和评估生物学特征的技术的最新进展,以及带有空间信息的细胞测量方法。文中还介绍了未来开发创新和方法所面临的挑战与机遇。

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本文引用的文献

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Tools for microbial single-cell genomics for obtaining uncultured microbial genomes.
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Heterogeneity of chemical modifications on RNA.
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3
Emerging tools for uncovering genetic and transcriptomic heterogeneities in bacteria.
Biophys Rev. 2024 Jan 2;16(1):109-124. doi: 10.1007/s12551-023-01178-y. eCollection 2024 Feb.
4
Integrating single-cell transcriptomics with cellular phenotypes: cell morphology, Ca imaging and electrophysiology.
Biophys Rev. 2023 Dec 18;16(1):89-107. doi: 10.1007/s12551-023-01174-2. eCollection 2024 Feb.
5
Progress in single-cell multimodal sequencing and multi-omics data integration.
Biophys Rev. 2023 Jul 15;16(1):13-28. doi: 10.1007/s12551-023-01092-3. eCollection 2024 Feb.
6
Representing and extracting knowledge from single-cell data.
Biophys Rev. 2023 Aug 5;16(1):29-56. doi: 10.1007/s12551-023-01091-4. eCollection 2024 Feb.
7
Studying temporal dynamics of single cells: expression, lineage and regulatory networks.
Biophys Rev. 2023 Aug 4;16(1):57-67. doi: 10.1007/s12551-023-01090-5. eCollection 2024 Feb.
8
Single-cell lineage tracing with endogenous markers.
Biophys Rev. 2024 Feb 7;16(1):125-139. doi: 10.1007/s12551-024-01179-5. eCollection 2024 Feb.

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