Tiki Yobsan Likasa, Tolesa Leta Deressa, Tiwikrama Ardila Hayu, Chala Tolesa Fita
College of Natural and Computational Science, Department of Chemistry, Ambo University, Ambo 19, Ethiopia.
College of Applied Natural Science, Department of Applied Chemistry, Adama Science and Technology University, Adama 1888, Ethiopia.
ACS Omega. 2024 Feb 27;9(10):11443-11452. doi: 10.1021/acsomega.3c07855. eCollection 2024 Mar 12.
Green synthesis of nanoparticles using plant extract is a novel development that has gained significant attention because of its low cost, nontoxicity, and environmental friendliness. In the present study, silver-doped stannic oxide (Ag-doped SnO) nanoparticle was synthesized by an eco-friendly green synthesis method. The synthesized samples were characterized using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), ultraviolet-visible spectroscopy (UV-vis), X-ray diffraction (XRD), and their antimicrobial activities were assessed against two bacteria () and () and two fungi () and () by using the disk diffusion method. Ag-doped SnO nanoparticles show a strong and broad absorption from UV-vis spectra when compared to pure SnO nanoparticles. FTIR spectral analysis revealed that the peak at 505.69 cm was assigned to Sn-O and O-Sn-O stretching vibration of SnO nanoparticles. XRD analysis confirmed the formation of a tetragonal rutile structure with average particle size ranging from 10 to 17 nm. The antimicrobial result indicates that the Ag-doped SnO revealed significant antimicrobial activity against both bacterial and fungi strains with the zone of inhibition of 29 ± 0.54, 27 ± 0.05, 17 ± 0.05, and 15 ± 0.05 mm for , , , and , respectively. Thus, the studies suggested that Ag-doped SnO nanoparticles exhibit good activity against both Gram-negative and Gram-positive bacteria and fungi. This is because doping SnO nanoparticles with metallic elements such as Ag has been used to enhance their performance, confirming them as a good candidate for antimicrobial agents and the development of future therapeutic agents.
利用植物提取物进行纳米粒子的绿色合成是一项新颖的进展，因其成本低、无毒且环境友好而备受关注。在本研究中，采用生态友好的绿色合成方法合成了银掺杂氧化锡（Ag掺杂SnO）纳米粒子。使用扫描电子显微镜（SEM）、傅里叶变换红外光谱（FTIR）、紫外可见光谱（UV-vis）、X射线衍射（XRD）对合成的样品进行了表征，并通过纸片扩散法评估了它们对两种细菌（）和（）以及两种真菌（）和（）的抗菌活性。与纯SnO纳米粒子相比，Ag掺杂SnO纳米粒子在UV-vis光谱中显示出强烈且宽泛的吸收。FTIR光谱分析表明，505.69 cm处的峰归属于SnO纳米粒子的Sn-O和O-Sn-O伸缩振动。XRD分析证实形成了四方金红石结构，平均粒径范围为10至17 nm。抗菌结果表明，Ag掺杂SnO对细菌和真菌菌株均显示出显著的抗菌活性，对、、和的抑菌圈直径分别为29±0.54、27±0.05、17±0.05和15±0.05 mm。因此，研究表明Ag掺杂SnO纳米粒子对革兰氏阴性菌、革兰氏阳性菌和真菌均表现出良好的活性。这是因为用诸如Ag等金属元素掺杂SnO纳米粒子已被用于提高其性能，证实它们是抗菌剂和未来治疗剂开发的良好候选者。
