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产超广谱β-内酰胺酶大肠埃希菌相关急性胆管炎：不常见的患者特征及临床意义

Extended-Spectrum Beta-Lactamase Escherichia coli-Associated Acute Cholangitis: Uncommon Patient Characteristics and Clinical Implications.

作者信息

Lee Somin, Qasim Abeer, Alemam Ahmed, Khaja Misbahuddin, Dev Anil

机构信息

Internal Medicine, BronxCare Health System, Icahn School of Medicine at Mount Sinai, Bronx, USA.

Internal Medicine, BronxCare Health System, Bronx, USA.

出版信息

Cureus. 2024 Feb 20;16(2):e54533. doi: 10.7759/cureus.54533. eCollection 2024 Feb.

DOI:10.7759/cureus.54533
PMID:38516487
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10956482/
Abstract

Acute cholangitis is a potentially life-threatening condition caused by an infection of the biliary tract resulting from biliary obstruction. This case report highlights an unusual presentation of acute cholangitis in an elderly patient characterized by the presence of extended-spectrum beta-lactamase-producing We aim to emphasize the significance of recognizing diverse clinical manifestations in the elderly population to enhance timely diagnosis and appropriate management. The case highlights the importance of better understanding patient risk factors for potential causative organisms and their susceptibility to selecting proper antibiotics and improving clinical outcomes.

摘要

急性胆管炎是一种由胆道梗阻导致的胆道感染引起的潜在危及生命的疾病。本病例报告强调了一名老年患者急性胆管炎的不寻常表现，其特征为存在产超广谱β-内酰胺酶的细菌。我们旨在强调认识老年人群中各种临床表现对于加强及时诊断和恰当治疗的重要性。该病例突出了更好地了解患者潜在致病生物的危险因素及其易感性对于选择合适抗生素和改善临床结局的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6609/10956482/b5e5e4ff075c/cureus-0016-00000054533-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6609/10956482/0ca20ff321f4/cureus-0016-00000054533-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6609/10956482/f081d5db5d3a/cureus-0016-00000054533-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6609/10956482/b5e5e4ff075c/cureus-0016-00000054533-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6609/10956482/0ca20ff321f4/cureus-0016-00000054533-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6609/10956482/f081d5db5d3a/cureus-0016-00000054533-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6609/10956482/b5e5e4ff075c/cureus-0016-00000054533-i03.jpg

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Extended-Spectrum Beta-Lactamase Escherichia coli-Associated Acute Cholangitis: Uncommon Patient Characteristics and Clinical Implications.产超广谱β-内酰胺酶大肠埃希菌相关急性胆管炎：不常见的患者特征及临床意义
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本文引用的文献

1
Use of microbiological and patient data for choice of empirical antibiotic therapy in acute cholangitis.利用微生物学和患者数据选择急性胆管炎的经验性抗生素治疗。
BMC Gastroenterol. 2020 Mar 12;20(1):65. doi: 10.1186/s12876-020-01201-6.
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Review of the Tokyo Guidelines 2018: Antimicrobial Therapy for Acute Cholangitis and Cholecystitis.《2018年东京指南：急性胆管炎和胆囊炎的抗菌治疗》述评
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Acute cholangitis: Diagnosis and management.急性胆管炎：诊断与管理。
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Cholangitis: Causes, Diagnosis, and Management.胆管炎：病因、诊断与治疗。
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5
Effect of Piperacillin-Tazobactam vs Meropenem on 30-Day Mortality for Patients With E coli or Klebsiella pneumoniae Bloodstream Infection and Ceftriaxone Resistance: A Randomized Clinical Trial.哌拉西林-他唑巴坦与美罗培南对产 ESBLs 的大肠埃希菌或肺炎克雷伯菌血流感染且对头孢曲松耐药患者 30 天死亡率的影响：一项随机临床试验。
JAMA. 2018 Sep 11;320(10):984-994. doi: 10.1001/jama.2018.12163.
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Tokyo Guidelines 2018: initial management of acute biliary infection and flowchart for acute cholangitis.东京指南 2018：急性胆道感染的初始管理和急性胆管炎的流程图。
J Hepatobiliary Pancreat Sci. 2018 Jan;25(1):31-40. doi: 10.1002/jhbp.509. Epub 2018 Jan 8.
7
Updated comprehensive epidemiology, microbiology, and outcomes among patients with acute cholangitis.急性胆管炎患者的最新综合流行病学、微生物学及预后情况
J Hepatobiliary Pancreat Sci. 2017 Jun;24(6):310-318. doi: 10.1002/jhbp.452. Epub 2017 May 26.
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Clinicomicrobiological analysis of patients with cholangitis.胆管炎患者的临床微生物学分析
Indian J Med Microbiol. 2014 Apr-Jun;32(2):157-60. doi: 10.4103/0255-0857.129802.
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TG13: Updated Tokyo Guidelines for the management of acute cholangitis and cholecystitis.TG13：更新的急性胆管炎和胆囊炎管理东京指南。
J Hepatobiliary Pancreat Sci. 2013 Jan;20(1):1-7. doi: 10.1007/s00534-012-0566-y.
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Extended Spectrum-β-Lactamase or Carbapenemase Producing Bacteria Isolated from Patients with Acute Cholangitis.从急性胆管炎患者中分离出的产超广谱β-内酰胺酶或碳青霉烯酶细菌
Clin Endosc. 2012 Jun;45(2):155-60. doi: 10.5946/ce.2012.45.2.155. Epub 2012 Jun 30.