Alhawari Hussein, Alzoubi Osama, Alshelleh Sameeha, Alfaris Leen, Abdulelah Mohammad, AlRyalat Saif Aldeen, Altarawneh Saleh, Alzoubi Mohammad
Department of Internal Medicine, Faculty of medicine, the University of Jordan, Amman, Jordan.
Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.
J Clin Hypertens (Greenwich). 2024 Dec;26(12):1368-1374. doi: 10.1111/jch.14801. Epub 2024 Mar 25.
Hypertension is a prominent risk factor for cardiovascular and cerebrovascular diseases. Gender differences and menopausal status contribute to blood pressure changes across the lifespan which have not been completely characterized. Our study aims to explore the impact of multiple factors on blood pressure levels in previously healthy women and men. Factors of interest included gender, menopausal status, age, and body mass index. Healthy women and men were recruited through healthcare facility announcements. Detailed menopausal history was obtained from females. The authors measured each participant's systolic and diastolic blood pressure at our outpatient clinics twice on the same day, and two different days, one week apart, and the authors included the mean of the averaged two readings for each participant. The study sample consisted of 313 participants. Female gender was a significant predictor of lower systolic and diastolic blood pressure (p < .001), while age significantly correlated with higher systolic blood pressure readings (p = .004). Although systolic blood pressure levels were significantly higher in postmenopausal females (124 mmHg) compared to premenopausal females (116 mmHg), our multiple linear regression analysis revealed that postmenopausal status did not significantly predict changes in either systolic or diastolic blood pressure. Our study demonstrates significant associations between blood pressure levels and various factors such as gender and age. This could emphasize the intricate interplay of demographic and clinical factors in blood pressure variations among individuals, highlighting the importance of a holistic approach to diagnosing hypertension, which considers various individual factors, including gender and age.
高血压是心血管和脑血管疾病的一个突出危险因素。性别差异和绝经状态会导致一生中血压的变化，而这些变化尚未完全明确。我们的研究旨在探讨多种因素对既往健康的女性和男性血压水平的影响。感兴趣的因素包括性别、绝经状态、年龄和体重指数。通过医疗机构公告招募健康的女性和男性。从女性那里获取详细的绝经史。作者在我们的门诊为每位参与者在同一天测量两次收缩压和舒张压，在相隔一周的两个不同日子测量，作者纳入了每位参与者两次测量平均值的均值。研究样本包括313名参与者。女性性别是较低收缩压和舒张压的显著预测因素（p <.001），而年龄与较高的收缩压读数显著相关（p =.004）。尽管绝经后女性的收缩压水平（124 mmHg）显著高于绝经前女性（116 mmHg），但我们的多元线性回归分析显示，绝经状态并不能显著预测收缩压或舒张压的变化。我们的研究表明血压水平与性别和年龄等各种因素之间存在显著关联。这可能强调了人口统计学和临床因素在个体血压变化中的复杂相互作用，突出了采用整体方法诊断高血压的重要性，这种方法要考虑包括性别和年龄在内的各种个体因素。
