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聚醚醚酮植入材料上玉米醇溶蛋白-硅酸钙复合材料涂层的研究与表征

Studying and Characterization of Coating of Zein-CaSiO Composite on Polyetheretherketone Implant Material.

作者信息

Abdulrazzaq Sama, Ismael Hamad Thekra

机构信息

Department of Prosthodontics, College of Dentistry, University of Baghdad, Baghdad, Iraq.

出版信息

Int J Dent. 2024 Mar 16;2024:1592439. doi: 10.1155/2024/1592439. eCollection 2024.

DOI:10.1155/2024/1592439
PMID:38524145
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10960650/
Abstract

Material-coated implants are placed in the bone and play an essential role in bone regeneration and rapid healing around implants. Polymeric matrix reinforced with ceramic materials is a promising composite material for coating implants. This study aims to determine the effect of mixing various concentrations of zein with CaSiO on polyetheretherketone (PEEK) as implant material. The coating was performed using the electrospray method. PEEK disks were used as a control group. The coated disks with different concentrations of zein-CaSiO (Group 1: 10% wt, 90% wt), (Group 2: 20% wt, 80% wt), and (Group 3%: 30% wt, 70% wt) were the experimental group. Each group was characterized by atomic force microscopy, field emission scanning electron microscope, Fourier-transform infrared spectroscopy, water contact angle, and adhesion strength. The lowest water contact angle was obtained for Group 1: 10% wt and 90% wt were (26.64° and 27.13°, respectively), and increasing amounts of zein in comparison to quantities of CaSiO resulted in increased adhesion strength of the composite material to the substrate. The current study suggested that the higher amount of zein compared to the amount of CaSiO mixture coating is achieved by electrospraying, a favorable candidate for coating implants compared to uncoated and coated disks with low concentrations of zein compared to concentrations of CaSiO.

摘要

材料涂层植入物被放置在骨中,在植入物周围的骨再生和快速愈合中起着至关重要的作用。用陶瓷材料增强的聚合物基体是一种很有前景的用于涂层植入物的复合材料。本研究旨在确定将不同浓度的玉米醇溶蛋白与硅酸钙混合对作为植入材料的聚醚醚酮(PEEK)的影响。采用电喷雾法进行涂层处理。PEEK盘用作对照组。含有不同浓度玉米醇溶蛋白 - 硅酸钙的涂层盘(第1组:10%重量,90%重量)、(第2组:20%重量,80%重量)和(第3组:30%重量,70%重量)为实验组。每组通过原子力显微镜、场发射扫描电子显微镜、傅里叶变换红外光谱、水接触角和粘附强度进行表征。第1组(10%重量和90%重量)获得了最低的水接触角(分别为26.64°和27.13°),并且与硅酸钙的量相比,玉米醇溶蛋白量的增加导致复合材料对基材的粘附强度增加。当前研究表明,通过电喷雾实现的与硅酸钙混合物涂层相比更高量的玉米醇溶蛋白,与未涂层和低浓度玉米醇溶蛋白与硅酸钙浓度相比的涂层盘相比,是一种用于涂层植入物的有利候选材料。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8656/10960650/144351b08f8b/IJD2024-1592439.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8656/10960650/916dcc0819b6/IJD2024-1592439.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8656/10960650/f694e9f48c34/IJD2024-1592439.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8656/10960650/2ebdc7fdeec8/IJD2024-1592439.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8656/10960650/5c1b6e862d3f/IJD2024-1592439.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8656/10960650/144351b08f8b/IJD2024-1592439.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8656/10960650/916dcc0819b6/IJD2024-1592439.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8656/10960650/f694e9f48c34/IJD2024-1592439.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8656/10960650/2ebdc7fdeec8/IJD2024-1592439.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8656/10960650/5c1b6e862d3f/IJD2024-1592439.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8656/10960650/144351b08f8b/IJD2024-1592439.005.jpg

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A programmed surface on polyetheretherketone for sequentially dictating osteoimmunomodulation and bone regeneration to achieve ameliorative osseointegration under osteoporotic conditions.聚醚醚酮上的一种程序化表面,用于依次调控骨免疫调节和骨再生,以在骨质疏松条件下实现改善的骨整合。
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