Zhao Xing, Chen Shiwen, Fan Yangyang, Lei Xianglan, Li Yulin, Ji Tianxing, Xia Hui, Wang Lu
College of Animal and Veterinary Sciences, Southwest Minzu University, Chengdu, Sichuan 610041, China.
College of Chemistry & Environment, Southwest Minzu University, Chengdu 610041, China.
ACS Omega. 2024 Mar 4;9(11):13183-13190. doi: 10.1021/acsomega.3c09620. eCollection 2024 Mar 19.
Nitrogen-doped carbon dots (NCD) with high fluorescence retention and good stability were successfully fabricated using citric acid and urea via a facile and eco-friendly one-step microwave method, which exhibited superior specificity for detection of nitrofurantoin (NFT). Upon the addition of NFT, the fluorescence intensity of NCD at 450 nm was significantly decreased. Besides, a satisfactory linear relationship between the fluorescence quenching efficiency and concentrations of NFT was obtained. Especially, NCD was qualitatively and quantitatively applied for detection NFT in milk and meat extract samples with a high recovery rate. Consequently, it was suggested that the detection method had potential application in the specific detection of NFT, offering a novel approach for veterinary drug residue detection.
采用柠檬酸和尿素，通过简便且环保的一步微波法成功制备了具有高荧光保留率和良好稳定性的氮掺杂碳点（NCD），其对呋喃妥因（NFT）的检测具有卓越的特异性。加入NFT后，NCD在450nm处的荧光强度显著降低。此外，荧光猝灭效率与NFT浓度之间获得了令人满意的线性关系。特别是，NCD被定性和定量应用于牛奶和肉类提取物样品中NFT的检测，回收率很高。因此，该检测方法在NFT的特异性检测中具有潜在应用，为兽药残留检测提供了一种新方法。
