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酵母细胞壁甘露聚糖的结构特征、生物活性及生产策略。

Yeast cell wall mannan structural features, biological activities, and production strategies.

作者信息

Baek Kwang-Rim, Rani Ramakrishnan Sudha, Kim Soo-Jung, Seo Seung-Oh

机构信息

Department of Food Science and Biotechnology, Seoul National University of Science and Technology, Seoul, 01811, Republic of Korea.

Department of Integrative Food, Bioscience, and Biotechnology, and Research Center for Biological Cybernetics, Chonnam National University, Gwangju, 61186, Republic of Korea.

出版信息

Heliyon. 2024 Mar 8;10(6):e27896. doi: 10.1016/j.heliyon.2024.e27896. eCollection 2024 Mar 30.

DOI:10.1016/j.heliyon.2024.e27896
PMID:38524613
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10958358/
Abstract

Mannan and outer structural yeast cell wall polysaccharides have recently garnered attention for their health defense and cosmetic applications. In addition, many studies have confirmed that yeast cell wall mannans exhibit various biological activities, such as antioxidant, immune regulation, reducing hyperlipidemia, and gut health promotion. This paper elucidates yeast cell wall mannan structural features, biological activities, underlying molecular mechanisms, and biosynthesis. Moreover, mannan-overproducing strategies through yeast strain engineering are emphasized and discussed. This review will provide a scientific basis for yeast cell wall mannan research and industrial applications.

摘要

甘露聚糖和酵母细胞外结构多糖最近因其健康防御和化妆品应用而受到关注。此外，许多研究证实，酵母细胞壁甘露聚糖具有多种生物活性，如抗氧化、免疫调节、降低高脂血症和促进肠道健康。本文阐述了酵母细胞壁甘露聚糖的结构特征、生物活性、潜在分子机制和生物合成。此外，还强调并讨论了通过酵母菌株工程提高甘露聚糖产量的策略。本综述将为酵母细胞壁甘露聚糖的研究和工业应用提供科学依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/340d/10958358/cc4ab5e45257/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/340d/10958358/288f9211f7de/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/340d/10958358/154952fe7968/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/340d/10958358/38d3c7876891/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/340d/10958358/cc4ab5e45257/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/340d/10958358/288f9211f7de/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/340d/10958358/154952fe7968/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/340d/10958358/38d3c7876891/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/340d/10958358/cc4ab5e45257/gr4.jpg

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