Sun Daming, Lo Kar Man, Chen Ssu-Chi, Leung Wing Wa, Wong Cherry, Mak Tony, Ng Simon, Futaba Kaori, Gregersen Hans
Engineering Research Center of Medical Electronics and Information Technology, Chongqing University of Posts and Telecommunications, Chongqing, China.
California Medical Innovations Institute, San Diego, CA, USA.
J Neurogastroenterol Motil. 2024 Jul 30;30(3):373-378. doi: 10.5056/jnm22177. Epub 2024 Mar 27.
BACKGROUND/AIMS: It is a common belief that constipated patients have hard feces that contributes to the difficulties defecating. To the best of our knowledge, no studies had been published on controlled evacuation of simulated feces with different consistencies.
Twelve normal subjects were recruited for studies with the simulated feces device "Fecobionics" of different consistency (silicone shore 0A-40A corresponding to Bristol stool form scale types 2-4). The subjects filled out questionnaires and had the balloon expulsion test and anorectal manometry done for reference. The Fecobionics probes were inserted in rectum in random order with +20 minutes between insertions. The bag was filled to urge-to-defecate and evacuations took place in privacy. Non-parametric statistics with median and quartiles are provided.
One subject was excluded due to technical issues, and another had abnormal anorectal manometry-balloon expulsion test. The 4 females/6 males subjects were aged 23 (range 20-48) years. Most differences were observed between the 0A and 10A probe (duration, maximum bag pressure, duration x maximum bag pressure, and relaxation of the front pressure and the bend angle during evacuation), eg, the duration was 9 (8-12) seconds at 0A and 18 (12-21) seconds at 10A ( < 0.05), and maximum bag pressure was 107 (96-116) cmHO at 0A and 140 (117-162) cmHO at 10A ( < 0.05). The bend angle before evacuation differed between the probes whereas only the 10A differed from 40A during defecation. The 10A was harder to evacuate than the 0A probe. Except for the bend angles, no further significant change was observed from 10A to 40A.
Fecal consistency affects defecatory parameters.
背景/目的:人们普遍认为便秘患者的粪便干结,这导致排便困难。据我们所知,尚未有关于不同硬度模拟粪便的可控排出情况的研究发表。
招募了12名正常受试者,使用不同硬度(对应布里斯托大便分类法2 - 4型的硅胶邵氏0A - 40A)的“粪便仿生学”模拟粪便装置进行研究。受试者填写问卷,并进行气球排出试验和肛肠测压以供参考。将粪便仿生学探头随机插入直肠,每次插入间隔20分钟。将袋子装满至有排便冲动后,受试者在私密环境中排便。提供中位数和四分位数的非参数统计数据。
一名受试者因技术问题被排除,另一名受试者肛肠测压 - 气球排出试验异常。4名女性/6名男性受试者年龄为23岁(范围20 - 48岁)。在0A和10A探头之间观察到了大多数差异(排便持续时间、最大袋内压力、排便持续时间×最大袋内压力以及排便时前压力和弯曲角度的松弛情况),例如,0A时排便持续时间为9(8 - 12)秒,10A时为18(12 - 21)秒(P < 0.05),0A时最大袋内压力为107(96 - 116)cmH₂O,10A时为140(117 - 162)cmH₂O(P < 0.05)。排便前弯曲角度在不同探头之间存在差异,而排便过程中只有10A与40A不同。10A比0A探头更难排出。除弯曲角度外,从10A到40A未观察到进一步的显著变化。
粪便硬度会影响排便参数。