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[西班牙脊髓灰质炎的根除:过去十年发生了什么?]

[Eradication of poliomyelitis in Spain: What has happened in the last decade?].

作者信息

Estrella-Porter Pablo, Fernández Dueñas Ana, Olmedo Lucerón Carmen, Cantero Gudino Elena, Limia Sánchez Aurora

机构信息

Servicio de Medicina Preventiva; Hospital Clínico Universitario de Valencia. Valencia. España.

Área de Programas de Vacunación; Ministerio de Sanidad. Madrid. España.

出版信息

Rev Esp Salud Publica. 2024 Mar 27;98:e202403028.

Abstract

On the 60 anniversary of the initiation of the polio vaccination campaign in Spain, the significant milestone in achieving disease control is highlighted. There has been a shift from an incidence of over 2,000 yearly cases in the 1960s to a sustained absence of wild poliovirus (WPV) since 1988. Despite the observed negative impact on polio vaccination coverage at the onset of the COVID-19 pandemic, these rates gradually recovered, reaching 98.2% in primary vaccination in 2022. Over the past decade, two essential elements have been identified to maintain the goal of polio elimination and that reinforces the importance of sustaining high vaccination coverage: robust epidemiological surveillance systems and a swift response to alerts to protect the vulnerable population and prevent virus reintroduction. In order to achieve eradication, it is crucial to interrupt international transmission and maintain continuous high-quality surveillance and effective coordination across different levels in response to any detection of PV, wild or vaccine derived. This article aimed to provide a comprehensive view of the polio eradication situation in Spain, focusing on the key events that occurred in the last decade and the present and future challenges.

摘要

在西班牙开展脊髓灰质炎疫苗接种运动60周年之际,实现疾病控制这一重要里程碑得到了凸显。脊髓灰质炎发病率已从20世纪60年代每年超过2000例转变为自1988年以来持续无野生脊髓灰质炎病毒(WPV)。尽管在新冠疫情初期观察到对脊髓灰质炎疫苗接种覆盖率产生了负面影响,但这些覆盖率逐渐恢复,2022年初级疫苗接种率达到98.2%。在过去十年中,已确定了两个维持脊髓灰质炎消除目标的关键要素,这强化了维持高疫苗接种覆盖率的重要性:强大的流行病学监测系统以及对警报迅速做出反应,以保护弱势群体并防止病毒重新引入。为了实现根除,至关重要的是中断国际传播,并在检测到任何野生或疫苗衍生脊髓灰质炎病毒时,维持不同层面持续的高质量监测和有效协调。本文旨在全面介绍西班牙的脊髓灰质炎根除情况,重点关注过去十年发生的关键事件以及当前和未来的挑战。

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