伤口修复与 Ca 信号转导的相互作用：Ca 通道在皮肤中的作用。

Dipartimento di Scienze e Innovazione Tecnologica (DiSIT), University of Piemonte Orientale, 15121 Alessandria, Italy.

SSD Laboratori di Ricerca-DAIRI, Azienda Ospedaliero-Universitaria SS. Antonio e Biagio e Cesare Arrigo, 15121 Alessandria, Italy.

Cells. 2024 Mar 11;13(6):491. doi: 10.3390/cells13060491.

The process of wound healing is intricate and tightly controlled, involving a number of different cellular and molecular processes. Numerous cellular functions, especially those related to wound healing, depend critically on calcium ions (Ca). Ca channels are proteins involved in signal transduction and communication inside cells that allow calcium ions to pass through cell membranes. Key Ca channel types involved in wound repair are described in this review.

伤口愈合的过程复杂而精细，受到多种不同的细胞和分子过程的严格控制。许多细胞功能，尤其是与伤口愈合相关的功能，严重依赖钙离子（Ca）。钙通道是参与细胞内信号转导和通讯的蛋白质，允许钙离子穿过细胞膜。本文综述了参与伤口修复的关键钙通道类型。