Zych-Krekora Katarzyna, Sylwestrzak Oskar, Krekora Michał, Oszukowski Przemysław, Grzesiak Mariusz
Department of Perinatology, Obstetrics and Gynaecology, Polish Mother's Memorial Hospital Research Institute, 93-338 Lodz, Poland.
Department of Obstetrics and Gynaecology, Polish Mother's Memorial Health Institute, 93-338 Lodz, Poland.
Biomedicines. 2024 Mar 14;12(3):654. doi: 10.3390/biomedicines12030654.
Developments in medicine and biology in recent decades have led to a significant increase in our knowledge of the complex interactions between the microbiota and human health. In the context of perinatal medicine and neonatology, particular attention is being paid to the potential impact of the maternal microbiota on fetal development. Among the many aspects of this relationship, the question of the impact of dysbiosis on the development of fetal heart defects is an important one. In this article, we present an analysis of recent research and scientific evidence on the relationship between a pregnant woman's microbiota and the development of fetal heart defects. We also discuss potential intervention strategies, including the role of probiotics and diet in optimising the maternal microbiota.
近几十年来，医学和生物学的发展使我们对微生物群与人类健康之间复杂相互作用的了解大幅增加。在围产期医学和新生儿学领域，母体微生物群对胎儿发育的潜在影响正受到特别关注。在这种关系的诸多方面中，菌群失调对胎儿心脏缺陷发育的影响问题是一个重要方面。在本文中，我们对近期关于孕妇微生物群与胎儿心脏缺陷发育之间关系的研究和科学证据进行了分析。我们还讨论了潜在的干预策略，包括益生菌和饮食在优化母体微生物群方面的作用。
