• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

巴西亚马逊地区蝙蝠体内病毒的鉴定：一项描述性宏基因组分析

Identification of Viruses in Bats from the Brazilian Amazon: A Descriptive Metagenomic Analysis.

作者信息

Pinheiro Lucas Rafael Santana, Rodrigues Érika Dayane Leal, Paiva Francisco Amilton Dos Santos, Cruz Ana Cecília Ribeiro, Medeiros Daniele Barbosa de Almeida, Casseb Alexandre do Rosário, Silva Sandro Patroca da, Casseb Livia Medeiros Neves

机构信息

Graduate Program in Virology, Hemorrhagic Fevers and Arbovirology Section (SAARB), Evandro Chagas Institute (IEC), BR-316 Highway, km 7, Levilândia, Ananindeua 67030-000, PA, Brazil.

Hemorrhagic Fevers and Arbovirology Section (SAARB), Evandro Chagas Institute (IEC), BR-316 Highway, km 7, Levilândia, Ananindeua 67030-000, PA, Brazil.

出版信息

Microorganisms. 2024 Mar 16;12(3):593. doi: 10.3390/microorganisms12030593.

DOI:10.3390/microorganisms12030593
PMID:38543644
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10974934/
Abstract

Bats are widely distributed in Brazil, including the Amazon region, and their association with viral pathogens is well-known. This work aimed to evaluate the metavirome in samples of sp. bats captured in the Brazilian Amazon from 2019 to 2021. Lung samples from 58 bats were divided into 13 pools for RNA isolation and sequencing followed by bioinformatic analysis. The family showed the highest abundance of viral reads. Although no complete genome could be recovered, the and families showed the formation of contigs with satisfactory identity and size characteristics for further analysis. One contig of the family was characterized as belonging to the genus , being grouped most closely phylogenetically to . The contig related to the family was identified within the genus, with 94%, 91%, and 42% amino acid identity with 2, , and , respectively. The presence of viruses in bats needs constant updating since the study was able to identify viral sequences related to families or genera still poorly described in the literature in association with bats.

摘要

蝙蝠广泛分布于巴西，包括亚马逊地区，并且它们与病毒病原体的关联是众所周知的。这项工作旨在评估2019年至2021年在巴西亚马逊地区捕获的 种蝙蝠样本中的宏病毒组。来自58只蝙蝠的肺样本被分成13个池用于RNA分离和测序，随后进行生物信息学分析。 科显示出病毒读数的丰度最高。尽管无法获得完整的基因组，但 科和 科显示出形成了具有令人满意的同一性和大小特征的重叠群，以便进行进一步分析。 科的一个重叠群被鉴定为属于 属，在系统发育上与 关系最为密切。与 科相关的重叠群在 属内被鉴定出来，与 2、 和 的氨基酸同一性分别为94%、91%和42%。由于该研究能够鉴定出与文献中仍描述较少的与蝙蝠相关的科或属相关的病毒序列，因此蝙蝠中病毒的存在情况需要不断更新。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/865a/10974934/f3c120f58862/microorganisms-12-00593-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/865a/10974934/dcc98dc7f448/microorganisms-12-00593-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/865a/10974934/4df5fc045e30/microorganisms-12-00593-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/865a/10974934/6345e05a4d7a/microorganisms-12-00593-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/865a/10974934/197936638ed1/microorganisms-12-00593-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/865a/10974934/8d73df650d5a/microorganisms-12-00593-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/865a/10974934/f3c120f58862/microorganisms-12-00593-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/865a/10974934/dcc98dc7f448/microorganisms-12-00593-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/865a/10974934/4df5fc045e30/microorganisms-12-00593-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/865a/10974934/6345e05a4d7a/microorganisms-12-00593-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/865a/10974934/197936638ed1/microorganisms-12-00593-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/865a/10974934/8d73df650d5a/microorganisms-12-00593-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/865a/10974934/f3c120f58862/microorganisms-12-00593-g006.jpg

相似文献

1
Identification of Viruses in Bats from the Brazilian Amazon: A Descriptive Metagenomic Analysis.巴西亚马逊地区蝙蝠体内病毒的鉴定：一项描述性宏基因组分析
Microorganisms. 2024 Mar 16;12(3):593. doi: 10.3390/microorganisms12030593.
2
Novel in Insectivorous Bats, from the Brazilian Amazon Region.来自巴西亚马逊地区食虫蝙蝠的新型病毒。
Viruses. 2023 Feb 22;15(3):606. doi: 10.3390/v15030606.
3
Metagenomic of Liver Tissue Identified at Least Two Genera of Totivirus-like Viruses in Bats.肝脏组织的宏基因组学研究在蝙蝠中鉴定出至少两个类全病毒属的病毒。
Microorganisms. 2024 Jan 19;12(1):206. doi: 10.3390/microorganisms12010206.
4
Krykféie dicistrovirus: A novel dicistrovirus in velvety free-tailed bats from Brazil.克里克菲伊双顺反子病毒：来自巴西绒蝠的一种新型双顺反子病毒。
Infect Genet Evol. 2019 Nov;75:104036. doi: 10.1016/j.meegid.2019.104036. Epub 2019 Sep 6.
5
Viral metagenomics of aphids present in bean and maize plots on mixed-use farms in Kenya reveals the presence of three dicistroviruses including a novel Big Sioux River virus-like dicistrovirus.肯尼亚混农区豆类作物和玉米田中蚜虫的病毒宏基因组学分析揭示了三种双分 RNA 病毒的存在，包括一种新型的大苏尔河病毒样双分 RNA 病毒。
Virol J. 2017 Oct 2;14(1):188. doi: 10.1186/s12985-017-0854-x.
6
Isolation and characterization of a novel cripavirus, the first Dicistroviridae family member infecting the cotton mealybug Phenacoccus solenopsis.一种新型杆状病毒的分离与鉴定，即首个感染棉红铃虫的 Dicistroviridae 科成员。
Arch Virol. 2020 Sep;165(9):1987-1994. doi: 10.1007/s00705-020-04702-7. Epub 2020 Jun 25.
7
Next-Generation Sequencing on Insectivorous Bat Guano: An Accurate Tool to Identify Arthropod Viruses of Potential Agricultural Concern.昆虫食蝙蝠粪便的下一代测序：一种准确识别潜在农业关注的节肢动物病毒的工具。
Viruses. 2019 Nov 28;11(12):1102. doi: 10.3390/v11121102.
8
Corona- and Paramyxoviruses in Bats from Brazil: A Matter of Concern?巴西蝙蝠中的冠状病毒和副粘病毒：值得关注吗？
Animals (Basel). 2023 Dec 26;14(1):88. doi: 10.3390/ani14010088.
9
Classification of new morbillivirus and jeilongvirus sequences from bats sampled in Brazil and Malaysia.从巴西和马来西亚采集的蝙蝠中新副黏病毒和杰伊龙病毒序列的分类。
Arch Virol. 2022 Oct;167(10):1977-1987. doi: 10.1007/s00705-022-05500-z. Epub 2022 Jul 4.
10
Bat guano virome: predominance of dietary viruses from insects and plants plus novel mammalian viruses.蝙蝠粪病毒组：以昆虫和植物来源的饮食相关病毒为主，还有新型哺乳动物病毒。
J Virol. 2010 Jul;84(14):6955-65. doi: 10.1128/JVI.00501-10. Epub 2010 May 12.

引用本文的文献

1
Evolutionary and structural basis of SLAMF1 utilization in morbilliviruses-Implications for host range and cross-species transmission.麻疹病毒中SLAMF1利用的进化和结构基础——对宿主范围和跨物种传播的影响
PLoS Pathog. 2025 Jun 10;21(6):e1012990. doi: 10.1371/journal.ppat.1012990. eCollection 2025 Jun.
2
Virome of Terrestrial Mammals and Bats from Southern Brazil: Circulation of New Putative Members of the Family and Other Findings.巴西南部陆生哺乳动物和蝙蝠的病毒组：该科新推定成员的传播及其他发现
Pathogens. 2025 Mar 24;14(4):310. doi: 10.3390/pathogens14040310.

本文引用的文献

1
Ultrafast one-pass FASTQ data preprocessing, quality control, and deduplication using fastp.使用fastp进行超快速单通道FASTQ数据预处理、质量控制和重复数据删除。
Imeta. 2023 May 8;2(2):e107. doi: 10.1002/imt2.107. eCollection 2023 May.
2
Virus Diversity, Abundance, and Evolution in Three Different Bat Colonies in Switzerland.瑞士三个不同蝙蝠群体中的病毒多样性、丰度和进化。
Viruses. 2022 Aug 29;14(9):1911. doi: 10.3390/v14091911.
3
Giant virus biology and diversity in the era of genome-resolved metagenomics.宏基因组学解析时代的巨型病毒生物学和多样性。
Nat Rev Microbiol. 2022 Dec;20(12):721-736. doi: 10.1038/s41579-022-00754-5. Epub 2022 Jul 28.
4
Classification of new morbillivirus and jeilongvirus sequences from bats sampled in Brazil and Malaysia.从巴西和马来西亚采集的蝙蝠中新副黏病毒和杰伊龙病毒序列的分类。
Arch Virol. 2022 Oct;167(10):1977-1987. doi: 10.1007/s00705-022-05500-z. Epub 2022 Jul 4.
5
Retroviruses of Bats: a Threat Waiting in the Wings?蝙蝠逆转录病毒：潜藏的威胁？
mBio. 2021 Oct 26;12(5):e0194121. doi: 10.1128/mBio.01941-21. Epub 2021 Sep 7.
6
Detection of multiple viruses in oropharyngeal samples from Brazilian free-tailed bats (Tadarida brasiliensis) using viral metagenomics.利用病毒宏基因组学检测巴西游离尾蝠（Tadarida brasiliensis）口咽部样本中的多种病毒。
Arch Virol. 2021 Jan;166(1):207-212. doi: 10.1007/s00705-020-04825-x. Epub 2020 Oct 12.
7
Six reference-quality genomes reveal evolution of bat adaptations.六份参考质量的基因组揭示了蝙蝠适应进化。
Nature. 2020 Jul;583(7817):578-584. doi: 10.1038/s41586-020-2486-3. Epub 2020 Jul 22.
8
Next-Generation Sequencing on Insectivorous Bat Guano: An Accurate Tool to Identify Arthropod Viruses of Potential Agricultural Concern.昆虫食蝙蝠粪便的下一代测序：一种准确识别潜在农业关注的节肢动物病毒的工具。
Viruses. 2019 Nov 28;11(12):1102. doi: 10.3390/v11121102.
9
ICTV Virus Taxonomy Profile: .ICTV 病毒分类学简介： 。
J Gen Virol. 2019 Dec;100(12):1593-1594. doi: 10.1099/jgv.0.001328. Epub 2019 Oct 11.
10
Krykféie dicistrovirus: A novel dicistrovirus in velvety free-tailed bats from Brazil.克里克菲伊双顺反子病毒：来自巴西绒蝠的一种新型双顺反子病毒。
Infect Genet Evol. 2019 Nov;75:104036. doi: 10.1016/j.meegid.2019.104036. Epub 2019 Sep 6.