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下颌黏液样脂肪肉瘤:病例研究

Mandibular Myxoid Liposarcoma: a Case Study.

作者信息

Barreras-Espinoza Jorge Arturo, López-Uribe Pamela Estefanía, Leyva-Moraga Francisco Alberto, Leyva-Moraga Fernando, Leyva-Moraga Eduardo, Ocejo-Gallegos Jesús Antonio, Burrola-Suárez Martín Armando, Burgos-Claudio Mónica I, Llanez-Grijalva Martha María, Martínez-Legorreta Ulises

机构信息

Department of Surgery, Hospital San Javier, Guadalajara, Jalisco Mexico.

Department of Surgery, Hospital General del Estado de Sonora, Hermosillo, México.

出版信息

Indian J Surg Oncol. 2024 Mar;15(Suppl 1):19-21. doi: 10.1007/s13193-023-01705-z. Epub 2023 Jan 21.

DOI:10.1007/s13193-023-01705-z
PMID:38545574
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10963671/
Abstract

Liposarcomas are described as soft tissue sarcomas derived from adipose tissue. The finding of this tumor in the mandibular region is exceedingly rare. As of now, it has been described mainly in case reports and small series. A multidisciplinary approach is required to offer optimal treatment and may involve surgery, radiation and systemic therapies. Surgical repair of these defects represents a major challenge in oral and maxillofacial reconstructive surgery. We present the case of a 54-year-old man referred to our center with a progressively increasing mass in the anterior portion of the mandible. Biopsy revealed a well-differentiated myxoid liposarcoma. Resection of the tumor was performed with an additional primary reconstruction.

摘要

脂肪肉瘤被描述为起源于脂肪组织的软组织肉瘤。在下颌区域发现这种肿瘤极为罕见。截至目前,它主要在病例报告和小系列研究中有所描述。需要多学科方法来提供最佳治疗,可能涉及手术、放疗和全身治疗。这些缺损的手术修复是口腔颌面重建手术中的一项重大挑战。我们报告一例54岁男性患者,因下颌前部肿物逐渐增大转诊至我院。活检显示为高分化黏液样脂肪肉瘤。对肿瘤进行了切除并同时进行了一期重建。

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本文引用的文献

1
Myxoid liposarcoma metastatic to the mandible: First case report and review of the literature.黏液样脂肪肉瘤转移至下颌骨:首例病例报告及文献复习
Oral Oncol. 2022 Jun;129:105900. doi: 10.1016/j.oraloncology.2022.105900. Epub 2022 May 4.
2
Myxoid pleomorphic liposarcoma-a clinicopathologic, immunohistochemical, molecular genetic and epigenetic study of 12 cases, suggesting a possible relationship with conventional pleomorphic liposarcoma.黏液样多形性脂肪肉瘤——12 例临床病理、免疫组织化学、分子遗传学和表观遗传学研究,提示其与传统多形性脂肪肉瘤可能存在一定关系。
Mod Pathol. 2021 Nov;34(11):2043-2049. doi: 10.1038/s41379-021-00862-2. Epub 2021 Jun 24.
3
Alternatives to free flap surgery for maxillofacial reconstruction: focus on the submental island flap and the pectoralis major myocutaneous flap.用于颌面重建的游离皮瓣手术替代方案:聚焦于颏下岛状皮瓣和胸大肌肌皮瓣。
BMC Oral Health. 2021 Apr 19;21(1):198. doi: 10.1186/s12903-021-01563-7.
4
Safety and efficacy of secondary mandibular reconstruction using a free osteo-cutaneous fibula flap after segmental mandibular resection: a retrospective case-control study.游离腓骨皮瓣重建下颌骨节段切除术后下颌骨的安全性和有效性:回顾性病例对照研究。
BMC Surg. 2021 Apr 9;21(1):189. doi: 10.1186/s12893-021-01194-3.
5
Well-differentiated liposarcoma and dedifferentiated liposarcoma: An updated review.高分化脂肪肉瘤和去分化脂肪肉瘤:最新综述。
Semin Diagn Pathol. 2019 Mar;36(2):112-121. doi: 10.1053/j.semdp.2019.02.006. Epub 2019 Feb 28.
6
The use of vascularized fibula flap in mandibular reconstruction; A comprehensive systematic review and meta-analysis of the observational studies.游离腓骨瓣在颌骨重建中的应用:观察性研究的系统评价和荟萃分析。
J Craniomaxillofac Surg. 2019 Apr;47(4):629-641. doi: 10.1016/j.jcms.2019.01.037. Epub 2019 Feb 1.
7
Diagnosis and Treatment of Myxoid Liposarcomas: Histology Matters.黏液样脂肪肉瘤的诊断与治疗:组织学很重要。
Curr Treat Options Oncol. 2018 Oct 25;19(12):64. doi: 10.1007/s11864-018-0590-5.
8
Myxoid Liposarcoma: Prognostic Factors and Metastatic Pattern in a Series of 148 Patients Treated at a Single Institution.黏液样脂肪肉瘤:在一家机构接受治疗的148例患者的预后因素和转移模式
Int J Surg Oncol. 2018 May 16;2018:8928706. doi: 10.1155/2018/8928706. eCollection 2018.
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BMC Cancer. 2018 Mar 20;18(1):304. doi: 10.1186/s12885-018-4226-8.
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Liposarcoma: Multimodality Management and Future Targeted Therapies.脂肪肉瘤:多模态管理与未来靶向治疗
Surg Oncol Clin N Am. 2016 Oct;25(4):761-73. doi: 10.1016/j.soc.2016.05.007. Epub 2016 Jul 30.