Sciberras Peter, Baitule Amey, Wilkins Alexander, Buchanan Alex
Surgery, Hull University Teaching Hospitals NHS Trust, Hull, GBR.
Pathology, Hull University Teaching Hospitals NHS Trust, Hull, GBR.
Cureus. 2024 Feb 28;16(2):e55165. doi: 10.7759/cureus.55165. eCollection 2024 Feb.
Tumours of the spleen are uncommon, and most are metastases from primaries in other organs. Primary splenic malignancies are subdivided into two main groups: lymphoid and non-lymphoid. Primary splenic cystadenocarcinomas are extremely rare, and only reports of the mucinous variant exist. We present the case of a female in her eighth decade of life who was found to have an incidental complex splenic mass with a cystic component, which showed an interval increase in size on serial imaging. After further investigation, including positron emission tomography (PET), endoscopic ultrasound (EUS), and laparoscopy, she successfully underwent distal pancreatectomy, splenectomy, and partial gastrectomy for a suspected locally invasive pancreatic malignancy. Histology and immunohistochemical analyses were consistent with the first recorded case of primary serous cystadenocarcinoma of the spleen in the literature.
脾脏肿瘤并不常见，大多数是其他器官原发性肿瘤的转移瘤。原发性脾脏恶性肿瘤主要分为两大类：淋巴类和非淋巴类。原发性脾囊腺癌极为罕见，仅有黏液性变体的报道。我们报告了一例八十多岁女性的病例，她偶然发现脾脏有一个伴有囊性成分的复杂肿块，在系列影像学检查中显示大小有间隔性增大。经过进一步检查，包括正电子发射断层扫描（PET）、内镜超声（EUS）和腹腔镜检查，她因疑似局部浸润性胰腺恶性肿瘤成功接受了远端胰腺切除术、脾切除术和部分胃切除术。组织学和免疫组化分析结果与文献中首例原发性脾脏浆液性囊腺癌的记录病例相符。
