Tej Pavan, Pareek Charu, Kalbande Avanti, Bawaskar Pranita A, Badge Ankit, Nair Nancy
Clinical Embryology, School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Obstetrics and Gynaecology, School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Cureus. 2024 Mar 1;16(3):e55323. doi: 10.7759/cureus.55323. eCollection 2024 Mar.
Infertility affects couples worldwide. Among these, obstructive azoospermia (OA) is a common cause. In some cases, the lack of spermatozoa in ejaculation results from blockages in the male reproductive tract. In this case study, we discuss an infertile male diagnosed with OA following three years of unsuccessful attempts at conception. The male had a history of bilateral inguinal hernia repair due to congenital bilateral absence of the vas deferens. Diagnostic assessments confirmed azoospermia. Microscopic epididymal sperm aspiration (MESA) was performed for sperm retrieval due to its efficacy and reduced postoperative pain, testicular atrophy, and decreased testosterone levels. The retrieved sperm was processed using SpermMobil media for intracytoplasmic sperm injection. Following successful fertilization, embryo transfers resulted in a positive pregnancy test. This case highlights the significance of specific treatment approaches for OA, specifically the effectiveness of MESA and SpermMobil in achieving successful outcomes in assisted reproduction technology for male infertility.
不孕不育影响着全球的夫妻。其中，梗阻性无精子症（OA）是一个常见原因。在某些情况下，射精中缺乏精子是由男性生殖道堵塞所致。在本病例研究中，我们讨论了一名不孕男性，其在三年的受孕尝试均未成功后被诊断为OA。该男性有因先天性双侧输精管缺如而行双侧腹股沟疝修补术的病史。诊断评估证实为无精子症。由于显微附睾精子抽吸术（MESA）具有疗效好、术后疼痛减轻、睾丸萎缩及睾酮水平降低风险小的特点，故采用该方法获取精子。获取的精子使用SpermMobil培养基进行处理，用于卵胞浆内单精子注射。成功受精后，胚胎移植导致妊娠试验呈阳性。本病例突出了针对OA的特定治疗方法的重要性，特别是MESA和SpermMobil在男性不育辅助生殖技术中取得成功结果方面的有效性。
