Park Junyong, Lee Sung Won
Division of Rheumatology, Department of Internal Medicine, Dong-A University Hospital, Busan, Korea.
J Rheum Dis. 2024 Apr 1;31(2):68-78. doi: 10.4078/jrd.2023.0084. Epub 2024 Feb 1.
Osteoarthritis (OA) is the most common form of arthritis, and its prevalence is expected to further increase as our society ages. Despite many approaches to cure OA, no drugs are currently proven to modulate the progression of OA. Nowadays, new OA treatment options are holistically developed and one of the approaches of treatment option is botanical drugs. Some botanical drugs for OA have shown both therapeutic effect comparable to refined drugs in small studies and fewer side effects. Hence, there are various health functional foods which are known to relieve symptoms of OA. However, since there are many botanical products, clinicians are not familiar to the efficacy of each botanical product, making it challenging to use them appropriately in clinical practice. Here, we summarize the botanical products available for treating OA, including prescription botanical drugs and health functional foods available in Korea. Further studies and the purification of effective molecules from botanical products will be necessary in future.
骨关节炎（OA）是最常见的关节炎形式，随着社会老龄化，其患病率预计还会进一步上升。尽管有许多治疗OA的方法，但目前尚无药物被证实可调节OA的进展。如今，新的OA治疗方案正在全面开发，其中一种治疗方法是植物药。一些用于OA的植物药在小型研究中已显示出与精制药物相当的治疗效果且副作用较少。因此，有各种已知可缓解OA症状的健康功能性食品。然而，由于植物产品众多，临床医生对每种植物产品的功效并不熟悉，这使得在临床实践中恰当地使用它们具有挑战性。在此，我们总结了可用于治疗OA的植物产品，包括韩国的处方植物药和健康功能性食品。未来有必要进行进一步的研究并从植物产品中纯化有效分子。
